To be fair this actually was an issue and came up again in The Babel Incident... it was (is?*) directly an opposition to God's command to multiply, fill the Earth and subdue it.
* One could argue that man has filled the whole world... kinda. This map, however, shows that the entire population of the world at [the city of] New York's population density would fill all of Texas and at the population density of Houston still wouldn't fill the entire US.
Really? Where does it say that in the Bible?
Genesis 11:1-9 (New Revised Standard Version)
Now the whole earth had one language and the same words. And as they migrated from the east, they came upon a plain in the land of Shinar and settled there. And they said to one another, Come, let us make bricks, and burn them thoroughly. And they had brick for stone, and bitumen for mortar. Then they said, Come, let us build ourselves a city, and a tower with its top in the heavens, and let us make a name for ourselves; otherwise we shall be scattered abroad upon the face of the whole earth.
The Lord came down to see the city and the tower, which mortals had built. And the Lord said, Look, they are one people, and they have all one language; and this is only the beginning of what they will do; nothing that they propose to do will now be impossible for them. Come, let us go down, and confuse their language there, so that they will not understand one anothers speech. So the Lord scattered them abroad from there over the face of all the earth, and they left off building the city. Therefore it was called Babel, because there the Lord confused the language of all the earth; and from there the Lord scattered them abroad over the face of all the earth.