[RandallFlagg]

You probably couldn't silence the revolver effectively due to the gap between the cylinder and barrel.

However, they're re-introducing the .44 Automag. (Click the pic)

[AFreeBird]

Try a Dan Wesson. The barrel is threaded on both ends. You can make the gap between cylinder and barrel very small. And the other end you could use the silencer in place of the nut for locking the barrel shroud on.

I think I heard the OSS used them (silenced in WWII). Though can’t be sure.