Ozone depletion was something we were supposed to have fixed. So it could be that it actually would have happened if we hadn’t taken steps against it. I don’t know the details, though.
Didn’t you hear? The ozone hole is back. Coincidentally, the patents will be running out soon on the HCFCs that replaced CFCs when their patents ran out.
The ozone hole over the South Pole is now bigger than Antarctica