"It had been insisted upon by those who were called anti-federalists, that this form of government consolidated the union; .... Those who were called anti-federalists at that time, complained that they were in favor of a federal government, and the others were in favor of a National one; the federalists were for ratifying the constitution as it stood, and the others did not until amendments were made [the Bill of Rights].Their names then ought not to have been distinguished by federalists and anti-federalists, but rats and anti-rats."Elbridge Gerry
That's a major stumbling block for people who dislike the national power. They believe that the Constitution is the solution, when in fact it's the problem. If you want limited government, anyway. If you like a big, honking, consolidated leviathan, then the Constitution is pretty good.