Any particular hotel?
The Grove Park Inn in Asheville, NC is notably haunted. Zelda Fitzgerald, the “pink lady,” possibly others.
The Marriott near the airport in New Orleans. I think it's the third floor there, if I remember correctly.
I think it was a Sofitel Hotel (?) in Rochester New York. I used to mark that one off my bid sheet after one night in that hotel. Although, I'm not entirely sure if that was a haunted hotel or just a pervert watching me while I was sleeping.
I stayed in the Hotel Congress in Tucson and didn't have any experiences, but a friend of mine had his mattress flipped onto the floor there-with him still on it.
And I've heard things about a hotel in Hartford, Connecticut. Also a beautiful old hotel in San Antonio. These are all things I've heard second-hand.