Zeugma is on the Euphrates River in SE Turkey not far from the Syrian border, 12 km north of the town of Birecik. It was founded by King Seleucus I, founder of the Seleucid Empire (ruled 323-281 B.C.). Because of its location it continued to be an important economic and military center during the Roman Empire and a Roman legion was stationed there.
Actually, I'm in Texas.