Ping for your interest
Merck, a company that manufacturers Ivermectin have also advised against its use in Covid-19 situations.
“Company scientists continue to carefully examine the findings of all available and emerging studies of Ivermectin for the treatment of Covid-19 for evidence of efficacy and safety. It is important to note that, to-date, our analysis has identified: No scientific basis for a potential therapeutic effect against Covid-19 from pre-clinical studies; No meaningful evidence for clinical activity or clinical efficacy in patients with Covid-19 disease, and; A concerning lack of safety data in the majority of studies,” the company said in a statement earlier this year.
The science vindicates the Government of Goa:
Review of the Emerging Evidence Demonstrating the Efficacy of Ivermectin in the Prophylaxis and Treatment of COVID-19
Kory, Pierre MD1,*; Meduri, Gianfranco Umberto MD2; Varon, Joseph MD3; Iglesias, Jose DO4; Marik, Paul E. MD5Author Information
1Front-Line Covid-19 Critical Care Alliance, Madison, WI;
2Memphis VA Medical Center—University of Tennessee Health Science Center, Pulmonary, Critical Care, and Research Services, Memphis, TN;
3University of Texas Health Science Center, Critical Care Service, Houston, TX;
4Department of Medicine, Hackensack School of Medicine, Seton Hall, NJ; and
5Eastern Virginia Medical School, Division of Pulmonary and Critical Care, Norfolk, VA.
*Address for correspondence: Pierre Kory, MD, MPA, Front-Line Covid-19 Critical Care, 2002 L St NW, Suite 500, Washington, D.C 20036. E-mail: pkory@flccc.net
G. U. Meduri’s contribution is the result of work supported with the resources and use of facilities at the Memphis VA Medical Center. The contents of this commentary do not represent the views of the US Department of Veterans Affairs or the US Government.
The authors have no conflicts of interest to declare.
P. Kory and G. U. Meduri have contributed equally to this work.
Study conception and design: P. Kory and G. . Meduri. Acquisition of data: Paul Marik and Jose Iglesias. Analysis and interpretation of data: Paul Marik, P. Kory, and Jose Iglesias. Drafting of manuscript: P. Kory. Critical revision: G. U. Meduri and Joseph Varon.
Off-Label Use: This manuscript includes discussion of off-label use in COVID-19 of the FDA-approved medication ivermectin.
This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
American Journal of Therapeutics: May/June 2021 - Volume 28 - Issue 3 - p e299-e318
doi: 10.1097/MJT.0000000000001377
Abstract
Background:
After COVID-19 emerged on U.S shores, providers began reviewing the emerging basic science, translational, and clinical data to identify potentially effective treatment options. In addition, a multitude of both novel and repurposed therapeutic agents were used empirically and studied within clinical trials.
Areas of Uncertainty:
The majority of trialed agents have failed to provide reproducible, definitive proof of efficacy in reducing the mortality of COVID-19 with the exception of corticosteroids in moderate to severe disease. Recently, evidence has emerged that the oral antiparasitic agent ivermectin exhibits numerous antiviral and anti-inflammatory mechanisms with trial results reporting significant outcome benefits. Given some have not passed peer review, several expert groups including Unitaid/World Health Organization have undertaken a systematic global effort to contact all active trial investigators to rapidly gather the data needed to grade and perform meta-analyses.
Data Sources:
Data were sourced from published peer-reviewed studies, manuscripts posted to preprint servers, expert meta-analyses, and numerous epidemiological analyses of regions with ivermectin distribution campaigns.
Therapeutic Advances:
A large majority of randomized and observational controlled trials of ivermectin are reporting repeated, large magnitude improvements in clinical outcomes. Numerous prophylaxis trials demonstrate that regular ivermectin use leads to large reductions in transmission. Multiple, large “natural experiments” occurred in regions that initiated “ivermectin distribution” campaigns followed by tight, reproducible, temporally associated decreases in case counts and case fatality rates compared with nearby regions without such campaigns.
Conclusions:
Meta-analyses based on 18 randomized controlled treatment trials of ivermectin in COVID-19 have found large, statistically significant reductions in mortality, time to clinical recovery, and time to viral clearance. Furthermore, results from numerous controlled prophylaxis trials report significantly reduced risks of contracting COVID-19 with the regular use of ivermectin. Finally, the many examples of ivermectin distribution campaigns leading to rapid population-wide decreases in morbidity and mortality indicate that an oral agent effective in all phases of COVID-19 has been identified.
We’d be using it here if Gates and Fauxi were big shareholders.
Defend is the key word Defend against WHAT?
Like I know the Indians have been using silver and gold for that matter for thousands of years to combat viruses bacteria and other pathogens
To me during this whole “crisis” which is merely a communist plot the media has gone all out trying to suppress inexpensive and widely available unpatentable and non-injectable carriers for COVID-19 such as intervention and hydroxychloroquine
Colloidal silver has been completely suppressed doesn’t even get mentioned in the media is much more effective and has been around for many many more hundreds and thousands of years combating affectively all viruses in all bacteria
Having been making this for over 40 years myself I watch the Internet completely change back to a complete suppression and the federal government tried to jump in anytime you would do a search for colloidal silver online
They cant stop the truth. Indians know the truth
Like I know the Indians have been using silver and gold for that matter for thousands of years to combat viruses bacteria and other pathogens
To me during this whole “crisis” which is merely a communist plot the media has gone all out trying to suppress inexpensive and widely available unpatentable and non-injectable carriers for COVID-19 such as intervention and hydroxychloroquine
Colloidal silver has been completely suppressed doesn’t even get mentioned in the media is much more effective and has been around for many many more hundreds and thousands of years combating affectively all viruses in all bacteria
Having been making this for over 40 years myself I watch the Internet completely change back to a complete suppression and the federal government tried to jump in anytime you would do a search for colloidal silver online
They cant stop the truth. Indians know the truth
You cant take it 5 days every day
You can take a loading dose ( 3-5 days depending on protocol selected)
Then take one dose biweekly
For prophylaxis
Usually recommended only if high risk