Posted on 06/10/2021 9:04:17 PM PDT by ConservativeMind
A British man who rejected the standard of care to treat his brain cancer has lived with the typically fatal glioblastoma tumor growing very slowly after adopting a ketogenic diet, providing a case study that researchers say reflects the benefits of using the body's own metabolism to fight this particularly aggressive cancer instead of chemo and radiation therapy.
Published recently in the journal Frontiers in Nutrition, the report is the first evaluation of the use of ketogenic metabolic therapy (KMT) without chemo or radiation interventions, on a patient diagnosed with IDH1-mutant glioblastoma (GBM). Ketogenic therapy is a non-toxic nutritional approach, viewed as complementary or alternative, that uses a low-carbohydrate, high-fat diet to manage a range of cancers, including glioblastoma.
In this particular case, the patient's tumor contained a mutation, known as the IDH1. This mutation is acquired by chance and is known to improve overall survival.
"In light of continued slow progression of the residual tumor, the patient intensified his KMT starting in October, 2018 with inclusion of mindfulness techniques to reduce stress. While Magnetic Resonance Imaging (MRI) shows slow interval tumor progression, the patient remains alive with a good quality of life at the time of this report." He is now at 82 months from original diagnosis.
"We were surprised to discover that KMT could work synergistically with the IDH1 mutation to simultaneously target the two major metabolic pathways needed to drive the growth of GBM," said Seyfried. "Glucose drives the glycolysis pathway, while glutamine drives the glutaminolysis pathway."
He added: "No tumor, including GBM, can survive without glucose and glutamine. Our study has identified a novel mechanism by which an acquired somatic mutation acts synergistically with a low-carbohydrate, high-fat diet to provide long-term management of a deadly brain tumor."
(Excerpt) Read more at medicalxpress.com ...
Remarkable. I’m a firm believer that everything we need to fight disease has been given to us, in the earth, by the LORD. In His mercy, he has also provided doctors and medicines, but forgoing carbohydrates is a walk in the park, compared to surgery, radiation, and chemo.
What is a ketogenic diet?
High fat very very low carbs. Its a challenge diet-wise. Without carbs the body shifts to making ketones for energy and much less glucose.
You cut out the bad Carbohydrates. Bread, pastas, rice, etc.
https://www.healthline.com/nutrition/ketogenic-diet-101
My wife has been telling people about this for 20 YEARS...more than a decade before anyone even heard of keto.
You don't really even need high fat diet, if you practice daily intermittent fasting...basically eat during only a 6 hr period of the day (while definitely avoiding carbs, preferring protein) and fast for 18 hrs.
Thanks.
Is oatmeal considered carbohydrate?
You forgot. No beer or wine.
Yes. Oatmeal is carbohydrates. Fat, oils and protein. The amount of carbs is limited to 50grams per day.
It’s hard on the kidneys and could lead to kidney failure. Should guzzle large amounts of water while on this diet.
I won’t reply to comments to this, so here it is:
The patient’s metabolism isn’t doing a damned thing: It’s all about the immune system.
Lucky for the patient the choices are working. But ‘keto’ is not panacea. In fact, ‘keto’ is dangerously myopic, particularly for someone with cancer.
But hey: If I didn’t have my current knowledge and developed brain cancer, I’d try anything, too.
Those curious about the link between diet and cancer should access and read this paper, which preceded the mad rush to profit off of people via ‘diet’ and medical therapies by a couple decades:
The cure of advanced cancer by diet therapy: a summary of 30 years of clinical experimentation
https://pubmed.ncbi.nlm.nih.gov/751079/
But the key is to avoid getting cancer in the first place, isn’t it? (rhetorical)
Plus the fact that this patient had a unique mutation in his cancer which happened to respond well to this self-treatment. 82 months post-diagnosis is nothing to shake a stick at, but he shouldn’t travel to Vegas in the belief that luck is on his side...nor should anyone with cancer blindly adopt a myopic dietary regimen in the mistaken belief that it’s going to cure what ails you...
I am guessing McCain didn’t have the IDH1 mutation or he could be Biden’s Sec State today.
“Keto can help fight some form of cancer in ways all other treatments cannot.”
No surprise here as cancers JUST LOVE glucose (i.e., carbs). Dr. Fung wrote a book on it. The hard part, actually, is trying to stay off carbs, particularly in settings where ‘nutritionists’ are involved, such as hospitals, because all they’re taught is to carb-load people.
Carbs are cheap.
Same problem in residential care facilities.
Back in the 1970s, actor Dirk Benedict (best known for the original Battlestar Galactica and The A-Team) had a prostate tumor and rejected conventional therapies in lieu of a macrobiotic diet. The tumor vanished and he’s still active at 76.
I like the South Beach diet bc it emphasizes seafood, but basically keto means cutting out or reducing sugars and carbs.
Carbs are needed for strenuous work - if the next day you intend to do much physical labor - like a farmer. Sugars
will make you hungrier faster, you’ll find them in almost everything, sugars feed cancers. I’ve researched and tried to minimize the sugar - best replacement is honey.
Also loads of benefits in bee pollen too. Only need a little so I put it in a grinder with garlic and other Italian seasonings.
Glutaminolysis, which catabolizes glutamine to generate ATP and lactate, is a metabolic pathway that involves the initial deamination of glutamine by GLS, yielding glutamate and ammonia.
There is a type of glioblastoma that is slow growing compared to the more common and aggressive form which is fast growing. The life expectancy for someone with the aggressive form, from time of diagnosis is 1-2 years while the less aggressive form can be up to 6 or more years.
Without or without KMT mindfulness techniques to reduce stress, he’d probably be at the same place he is now. But get back to me after 7 – 10 years and tell me if he survived.
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