Posted on 01/23/2023 1:55:42 PM PST by ConservativeMind
Brain structures which could predict an individual's predisposition to accidental awareness under anesthetic have been identified for the first time by neuroscientists.
The findings could help identify individuals who may require higher than average doses of anesthetic.
Although anesthesia has been used in clinical medicine for over 150 years, scientists do not fully understand why its effect on people is so varied. One in four patients presumed to be unconscious during general anesthesia may in fact have subjective experiences, such as dreaming, and in very rare cases (0.05–0.2%) individuals become accidentally aware during a medical procedure.
The research found that one in three participants were unaffected by moderate propofol sedation in their response times, thus thwarting a key aim of anesthesia—the suppression of behavioral responsiveness.
The research also showed, for the first time, that the participants who were resistant to anesthesia had fundamental differences in the function and structures of the fronto-parietal regions of the brain to those who remained fully unconscious. Crucially, these brain differences could be predicted prior to sedation.
"Our results suggest that individuals with larger gray matter volume in the frontal regions and stronger functional connectivity within fronto-parietal brain networks, may require higher doses of propofol to become nonresponsive compared to individuals with weaker connectivity and smaller gray matter volume in these regions."
The research, conducted in Ireland and Canada, investigated 17 healthy individuals who were sedated with propofol, the most common clinical anesthetic agent. The participants' response time to detect a simple sound was measured when they were awake and as they became sedated. Brain activity of 25 participants as they listened to a simple story in both states was also measured.
(Excerpt) Read more at medicalxpress.com ...
I have “woke up” in the middle of procedures on 3 different occasions.
This happened to me the last procedure.
I was billed $1,000 for one syringe and never felt a thing from it. Just that copper like taste of saline.
I was supposed to be getting versed and fentanyl.
They could have saved the me the money and given me a shot of scotch.
I woke up...partially...during a colonoscopy. There was no pain or anything but I did get to see the screen they used for the procedure.
if this has never happened to you before than possibly they gave you a placebo so someone could feed their own drug habit ?
I mean I personally have gotten fake stuff from Amazon before, and have read about people doing this to opioids in medical settings.
I had a dermatologist who I thought was always messed up on something, then a few years later I read in the paper how he was busted for getting a fake identity and writing scrips for himself.
I didn’t think about that possibility.
The hospital I was in has a reputation for ripping people off so I just chalked it up to that.
Good thing I have a high pain tolerance.
I would so totally date that redhead
yep.
I can tell that she is the perfect combo of hot/crazy who craves domination
Me too. Paralyzed but aware. It is very uncomfortable.
Easy, now!
Her name might be Tiffany.
It had no effect on me when I went for my first (and last) colonoscopy.
How about not totally paralyzed but fully aware and watching the surgery inside your own eye?!
And terrified to speak and startle the surgeon so vigorously wiggle some toes for someone to notice.
Then again years past waking up FIVE hours past the “normal”surgery recovery time to see TWO nurses anxiously watching .
Anethesia isnt exact science.
“Bad memories are better than no memories.” Redheaded women do take a lot.
A fellow I know is an AA sponsor. He is working right now with an Anesthesiologist who stole patient drugs.
There is a lot of confusion about general anesthesia. Most folks who report that they woke up during a procedure were receiving sedation, not general anesthesia. If they didn’t put a breathing tube down your throat you didn’t have general anesthesia. If you had an office procedure or colonoscopy you had sedation , not general anesthesia.
Twice I’ve woken up during major abdominal surgery while the tubes were in me and my arms were strapped to boards.
Even the Propofol didn’t work with me.
Same during a colostomy. Made the doc uncomfortable as I watched the screen and commented during the procedure.
I also couldn’t stand the epidural analgesia. Had them disconnect it immediately after surgery and give me IV Tylenol.
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