Posted on 09/16/2023 7:32:32 AM PDT by ConservativeMind
UCI researchers have found that a simple sugar, N-acetylglucosamine, reduces multiple inflammation and neurodegeneration markers in people who suffer from multiple sclerosis (MS). In addition, they also found this dietary supplement improved neurological function in 30% of patients.
A major issue with current therapies in MS is the inability to treat chronic-active neuroinflammation in the brain and the associated failure to repair the loss of myelin that covers and protects axons, the electrical wires of the brain. Over time, this leads to permanent nerve cell damage and slow progressive loss of neurological function in patients.
"Our previous studies in mice and humans implicated N-acetylglucosamine in suppressing brain inflammation, promoting the regrowth of the myelin sheath and slowing brain degeneration," said Michael Demetriou, MD, Ph.D.
The new paper reports on the first clinical trial of N-acetylglucosamine in MS patients to directly investigate these potential activities.
Researchers found that N-acetylglucosamine was safe and reduced multiple inflammation and neurodegeneration markers in MS patients despite the patients already being on the FDA approved immunomodulatory therapy Glatiramer Acetate, known to impact these pathways outside the brain.
"We also observed a sustained reduction in neurological disability in 30% of the patients, an activity which has not been observed with current FDA-approved therapies," said Michael Y. Sy, MD, Ph.D. "They at best slow progression, not improve function."
The data suggest that N-acetylglucosamine reduced untreated chronic-active neuroinflammation and/or promoted myelin repair. However, the researchers stress that the trial was unblinded and therefore future blinded studies and additional parameters are essential to validate N-acetylglucosamine's potential to improve residual chronic-active brain inflammation, myelin repair, neurodegeneration and neurological function in MS.
(Excerpt) Read more at medicalxpress.com ...
If you , or anyone you know, is having trouble with brain function, and they’re taking statins, tell them to stop the statins. The myelin is made of cholesterol which statins destroy. In other words, they no longer have insulation around the wiring. This happened to me. I couldn’t put a sentence together. Fortunately I was able to trace my troubles back to when I started taking the statins and stopped cold turkey. Within a week I was back to normal. My doctor was mad at me. A bit of research explained it to me, and my NEW doctor said it happens to a lot of people.
SAVE
Is this the same as the OTC supplement N-A-G?
N-A-C
NAC is N-acetyl-cysteine. That’s not the same, is it? I read it affects glutathione, though.
save for later.
Something more dramatic happened to an acquaintance of mine. He is in his mid 70s. He is an avid bicyclist and very thin. His doctor put him on statins. Within a month he was in a wheelchair and had mental fog. His doctor refused to take him off statins. He got a new doctor and the new doctor immediately took him off statins. Within two months he was using a walker and he mental fog was dissipating. It took almost a year, but he is back to his usual self.
Man thanks for your post.
Isnt NAC - N-ACETYL CYSTEINE?
These are examples of the supplements:
Source Naturals:
https://www.amazon.com/Source-Naturals-N-Acetyl-Glucosamine-Supplement/dp/B000EQ6H1Q
Bulk Supplements:
https://www.amazon.com/N-Acetyl-D-Glucosamine-BulkSupplements-Digestive-Support/dp/B074JHM2NB
Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.