Persistent fluorinated chemicals tied to higher risk for inflammatory bowel disease

Medical Xpress / HealthDay / Clinical Gastroenterology and Hepatology ^ | Jan. 12, 2024 | Lori Solomon / Manasi Agrawal et al

[ConservativeMind]

Perfluoroalkyl and polyfluoroalkyl substance (PFAS) exposure is associated with later occurrence of inflammatory bowel disease (IBD), according to a research letter.

Manasi Agrawal, M.D. and colleagues examined the association of PFAS mixture concentrations in prediagnostic serum in patients with adult-onset IBD participating in a pilot study within the preclinical Proteomic Evaluation and Discovery in an IBD Cohort of Tri-service Subjects study. The analysis included military personnel with Crohn disease (CD), those with ulcerative colitis (UC), and age-, sex-, and race-matched healthy controls (25 in each group).

The researchers found that estimated mean concentrations in the study population were 5.19 µg/L for perfluorooctane sulfonic acid, 2.57 µg/L for perfluorooctanoic acid, and 2.32 µg/L for perfluorohexane sulfonate, which were comparable to PFAS levels in the general U.S. population. Within one year of diagnosis, each one-unit increase in decile mixture of fluorinated compounds in serum samples, including the known PFAS, was associated with higher odds of CD and UC (odds ratios, 2.13 and 1.76, respectively). At all four time points up to 10 years prior to diagnosis, these associations persisted for the PFAS mixture for both CD and UC.

"Studies in larger cohorts, including analyses of pathways perturbed due to PFAS and the impact of new PFAS on disease outcomes, will be informative toward understanding IBD pathways and developing health policies to minimize exposure to harmful chemical pollutants," the authors write.

[ConservativeMind]

An easy way to get rid of PFAS is to donate blood.

To prevent it from building up, water filters with catalytic carbon can do a great job. NSF has certified some filters for these substances.

[ConservativeMind]

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[albie]

No shit

[griffin]

Know when fluoridation first began? 1946.

https://m.youtube.com/watch?v=eB5Vvs2cdqY&fbclid=IwAR2oxR2pP174khpJ5OX6-karo7LLuhwKZhCykxBlc3d-G7JireIRmSUOPGg

[griffin]

Know when fluoridation first began? 1946.
https://m.youtube.com/watch?v=eB5Vvs2cdqY&fbclid=IwAR2oxR2pP174khpJ5OX6-karo7LLuhwKZhCykxBlc3d-G7JireIRmSUOPGg

[Boomer]

Not just flouridation but chlorination too. The germ killer they put in tap water also kills the good germs in my gut. Ever since I started using a good filter system for my drinking water, the diagnosed UC wen away and hasn’t come back. I suspect I found and treated the cause instead of just the symptom. This may not be what the cause is for others but it is what it was for me. It does make me wonder what percentage of the population is also affected the same way though. I think I’m also sensitive to chlorine/bromine. Not allergic, just sensitive so I need to limit my exposure to these chemicals. It doesn’t affect me in the shower.

[fruser1]

[ChessExpert]

For the sake of argument, let’s accept the claim that fluoride strengthens teeth. Topical application to the teeth would seem to make sense. Putting fluoride in the water you drink, use for cooking, and shower/bath in, with the hope that some fluoride would make it to your teeth, makes far less sense.

Many people have thyroid problem and in some cases it may be due to Fluoride. Fluorine is in the same chemical family as Iodine.
https://pubchem.ncbi.nlm.nih.gov/periodic-table/
Iodine is used by the thyroid to make the T3 and T3 hormones that control your metabolism. T3 has three Iodine atoms, T4 four. If an iodine receptor is clogged with fluorine then it can’t accept iodine.

I’ve installed a reverse osmosis water purifier for drinking water. It takes out everything. Unfortunately, it also takes out calcium and magnesium which are good for your bones. So, I have recently added another cannister to the water system to re-introduce minerals to my drinking water.

[dfwgator]

You ever see a Commie drink a glass of water?

[DaiHuy]

Unfortunately, it also takes out calcium and magnesium...

Magnesium is also needed to regulate blood pressure. Since I started taking Magnesium my BP has gone into the normal range.

[e_castillo]

Good movie!