Posted on 02/03/2024 7:58:22 PM PST by ConservativeMind
People with ischemic (clot-caused) stroke had better early recovery of cognitive function if treated with intravenous injections of a combination of biologically active components of ginkgo biloba during the first two weeks after the stroke, according to a preliminary study.
In early 2023, researchers from this study published the results of a multicenter trial indicating that people with ischemic stroke had better recovery if they were treated with daily injections of ginkgo diterpene lactone meglumine (GDLM), a combination of the biologically active components of ginkgo biloba.
The researchers analyzed the cognitive recovery of 3,163 stroke survivors (average age of 63 years; 36% women) treated for mild to moderate ischemic stroke at 100 centers in China. Starting within 48 hours of the stroke, about half of the stroke survivors were randomly selected to receive daily, intravenous injections of 25 mg of GDLM for 14 days, while the other half received daily, intravenous placebo injections.
Cognitive performance was assessed before treatment, at 14 days and at 90 days using the Montreal Cognitive Assessment scale (MoCA), a 30-point face-to-face screening test of cognitive performance often used with stroke survivors.
Compared to their initial cognitive screening results:
By day 14, stroke survivors who received the ginkgo biloba compound injections had improved cognitive scores in comparison to those who received the placebo (an average of 3.93 points vs. 3.62 points higher, respectively); and
By day 90, those who received the ginkgo biloba compound injections had even more improved cognitive scores compared to those who received the placebo (an average of 5.51 points vs. 5.04 points).
"The proportion of patients who reached a clinically significant level of improvement was 20% higher in the GDLM group, indicating that GDLM injections may improve cognitive function in patients with acute ischemic stroke," Wang said.
(Excerpt) Read more at medicalxpress.com ...
And you might develop the powers of Elastic Man.
LOL!
My husband sings Gingko biloba to the tune of https://m.youtube.com/watch?v=O4_5593-skQ&pp=ygUaYmUtYm9wLWEtbHVsYSBnZW5lIHZpbmNlbnQ%3D
Every time he hears someone say it. And it fits perfectly.
Thank you for posting this interesting article. 🙏
“The primary outcome on day 90 occurred in 877 patients (50.8%) in the GDLM group, and 759 patients (44.1%) in the placebo group (risk difference, 6.79%; 95% CI, 3.46%-10.10%; odds ratio, 1.31; 95% CI, 1.15-1.50; relative risk, 1.15; 95% CI, 1.08-1.24; P < .001).
Adverse events occurred relatively equally between the 2 groups (303 [17.6%] vs 298 [17.3%]”
Efficacy and Safety of Ginkgo Diterpene Lactone Meglumine in Acute Ischemic Stroke;
A Randomized Clinical Trial
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425831/
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