Higher vitamin D levels found to cut bowel resection risk with IBD

Medical Xpress / HealthDay / International Journal of Surgery ^ | April 4, 2024 | Lori Solomon / Lintao Dan et al

[ConservativeMind]

An increased serum level of 25-hydroxyvitamin D (25[OH]D) is independently associated with a lower risk for bowel resection with inflammatory bowel disease (IBD), according to a study.

Lintao Dan and colleagues examined the association between serum vitamin D levels and the risk for bowel resection in individuals with IBD. The analysis included 5,474 individuals with IBD followed for a mean 13.1 years.

The researchers found that compared with participants with vitamin D deficiency, nondeficient participants showed a significantly reduced bowel resection risk in IBD (hazard ratio [HR], 0.72), Crohn disease (CD; HR, 0.74), and ulcerative colitis (UC; HR, 0.73).

For the highest versus lowest quintiles of 25(OH)D level, there was a 34 percent reduced risk for bowel resection with IBD and a 46 percent reduced risk with UC; these findings were statistically significant. However, there were no significant associations for risk for bowel resection in CD. Linear dose-response associations were seen using the restricted cubic spline curve.

"Vitamin D deficiency is a risk factor for bowel resection in individuals with IBD, and may be an effective metric in predicting and risk-screening surgical events," the authors write.

[ConservativeMind]

It appears a good Vitamin D status could indicate IBD risk for the need for a resection goes down.

[ConservativeMind]

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[telescope115]

That’s good to know! Along with everything else I take, I also take a multivitamin, drink lactose free milk, and get sunshine when I can (more in the spring and summer).

[roving]

I have colitis. If I don’t take vitamin D I’ll be depleted.