This is a big concern right now, as my son is getting ready to tackle High School and I want to make sure he is on the right track.
Just to pass on a Show Me state experience, I have a young friend (19) who was homeschooled his entire life. Went and took his GED and ACT, and got such high scores the local community college gave him a full academic scholarship. After he graduates here he's going toward pre-med as he wants to be a pediatric opthamologist.