Not much, actually.
These systems are good for single-mission aircraft, where we dont care much whether or not the aircraft comes back. When decisions and adjustments need to me made during a mission, you really need a man in the cockpit. Air to Air Combat will likely always require a man, because you could probably never duplicate SA (Situational Awareness) with a computer.
Besides, who would ever join the Navy, except for the opportunity to fly a hot-rod? I sure as hell didnt sign up for the food and benefits.
Prediction: inside of 15 years, there will be no more fighter pilots. The machines will be too cheap and too lethal. Whether or not machine pilots are the "equal" of human pilots by that time (they will be eventually), the survivability of a combat mission will drop to something very low.