Try a 10mm, you won't be sorry. It's a highly versatile, and compact round that stows well in a semi-automatic pistol.
I own a Glock 20C for hunting, and a Glock 29 for concealed carry. I like them alot.
Glocks don't fit my hands very well. They feel awkward. I've got very large hands so it takes a really big set of grips on a gun to get a comfortable handle on a pistol.
The singular most comfortable feeling gun I've ever picked up was the .44 Desert Eagle. Like it was molded to my hand.