nah, the engines just fell off by themselves ... happens all the time ... [/sarcasm]
Chicago, 1979. American 191. That's exactly what happened.
On May 25, 1979, an American Airlines DC-10-10, Registry N110AA crashed due to just that. As the aircraft began its rotation, the Number 1 (port) engine and pylon separated from the aircraft. It flew up and over the wing ripping out fuel and hydraulic lines. This caused the slats on the left wing to retract. When the crew followed the standard procedure for an engine failure, they reduced power on engines 2 & 3. This caused airspeed to drop and due to the asymmetrical slats caused by the engine tearing away, the left wing stalled and N110AA fell to earth killing all 270 people on board and 2 on the ground.
Remember the Electra? Beautiful plane. Wings broke off, though. Those planes were pulled from service.
I remember it happening to some plane in ... Chicago? In the 70s? Somebody got a picture of it right after, and before it reached the ground -- you could tell by the attitude (orientation) of the plane in the photo that it was in big trouble...