It might convert Iran from 55,000,000 pro-western and 5,000,000 Arabists to 60,000,000 Arabists overnight. Of course, many (if not most) in the Middle East (rightly or wrongly) see Israel as the 51st state of the US.
How will the Commonwealth of Independent States take to having their technicians attacked?
Despite a lot of bluster, they took Beslan pretty much lying down.
You seem to believe in the existence of 'moderate Islam'. I've heard a lot about it, but I find experimental proof lacking. There are a lot of Iranians who want to be able to import soft porn and shed the burqas. I'm not sure there are a lot who are willing to tolerate the existence of Israel or to argue when the local goons yell 'death to America'.
If Israel can do the job with precision-guided conventional munitions, I say, go for it. It would be more efficient with tactical nukes, which Israel certainly has, but probably the international wailing and gnashing of teeth would be best avoided.
Me, I don't think there's a majority Islamic state that should be allowed to have matchlocks, but one step at a time.