You leave the area ASAP.
I think I've read that in a recent simulation, the F-22 was at least 10 times more likely to survive all known threats in any given area than the F-15. When you are a U.S. Marine on the ground, having the skies over you dominated by however many F-22's has to be important. I understand that most fighter pilots want them because they are very, very hard to shoot down with SAM's.
The F-22's role isn't close air support. That's supposed to be the job of the F-35 JSF.