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Strands of DNA Make Nano-Smiley
Discovery.com ^ | March 15th, 2006 | Unknown

Posted on 03/20/2006 8:08:31 AM PST by Termite_Commander

A nanotechnologist has created the world's smallest and most plentiful Smiley, a tiny face measuring a few billionths of a meter across that is assembled from strands of DNA.

Fifty billion Smileys, each a thousand times smaller than the diameter of a human hair, can be made at a stroke under the technique pioneered by Paul Rothemund at the California Institute of Technology (Caltech).

DNA, the molecule that comprises living things, has long been known for its versatility as a microscopic building block.

The molecule can be "cut" using enzymes and reassembled using matching rungs in its double-helix structure. This theoretically opens the way to making DNA quantum computers and nano-level devices including injectable robots that can monitor the body's tissues for good health.

But until now, nano-assembly has been a complex atom-by-atom procedure that is also costly, because it is carried out in a vacuum or at extremely cold temperatures.

Rothemund, writing in Thursday's issue of Nature, describes a far simpler and much cheaper process in which long, single strands of DNA can be folded back and forth to form a basic scaffold.

The basic structure is then supplemented by around 200 shorter strands, which both strengthen it and act rather like pixels in a computer or TV image, thus providing a shape that can bear a complex pattern.

In a potent demonstration of his so-called DNA oragami technique, Rothemund has created half a dozen shapes, including a five-pointed star, a snowflake, a picture of the double helix and a map of the Americas in which one nanometer (one billionth of a meter) represents 120 kilometers (70 miles).

Rothemund has been working on flat, two-dimensional shapes, but says that 3-D structures in DNA should be quite feasible with this technique, Caltech said in a press release.

One application would be a nano-scale "cage" in which pharmaceutical researchers, working on novel drugs, could sequester enzymes until they were ready for use in turning other proteins on and off.

"In this research, Paul has scored a few unusual 'firsts' for humanity," his colleague, Erik Winfree, said. "In a typical reaction, he can make about 50 billion Smiley faces. I think this is the most concentrated happiness ever created."

Winfree said there could be huge potential benefits from this apparently whimsical work, as it provided a major new tool for putting molecular-level machinery together.


TOPICS: Miscellaneous
KEYWORDS:
Go figure.
1 posted on 03/20/2006 8:08:32 AM PST by Termite_Commander
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To: Termite_Commander

:)


2 posted on 03/20/2006 8:09:47 AM PST by Liberal Classic (No better friend, no worse enemy. Semper Fi.)
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To: Termite_Commander
Related thread with pictures
3 posted on 03/20/2006 8:10:49 AM PST by martin_fierro (< |:)~)
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To: Termite_Commander
And here it is:


4 posted on 03/20/2006 8:11:19 AM PST by MineralMan (godless atheist)
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To: martin_fierro
Oops. Guess I should have searched a bit more thoroughly.
5 posted on 03/20/2006 8:12:43 AM PST by Termite_Commander (Warning: Cynical Right-winger Ahead)
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To: Termite_Commander

"I think this is the most concentrated happiness ever created."


Uh huh...


6 posted on 03/20/2006 8:14:10 AM PST by null and void (Sept 11th: National Moderate Muslim Day of Tacit Approval)
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To: MineralMan

Heck, I invented these about 30 years ago but hey were too small and no-one could see them.

Kind regards


7 posted on 03/20/2006 8:14:23 AM PST by vimto ("I've seen the future of Islam, Guess what? We won!")
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To: MineralMan

godless atheist?

Is there any other kind?

warm regards,


8 posted on 03/20/2006 8:16:23 AM PST by vimto ("I've seen the future of Islam, Guess what? We won!")
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To: vimto

actually atheists do have a god...

-'Self' is his name


9 posted on 03/20/2006 9:06:05 AM PST by joesnuffy (A camel once bit our sister..but we knew just what to do...we gathered rocks and squashed her!)
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