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The Blood Cleaner [device filters viruses from circulating blood]
Popular Science ^ | March 2006 | David Kohn

Posted on 04/09/2006 5:53:21 PM PDT by AntiGuv

No bigger than a pen, this device filters smallpox, Ebola and other viruses from the blood

It is a prospect that terrifies bioweapons experts: Terrorists release smallpox into an American city, spreading sickness and panic. Because the disease is untreatable and vaccines no longer exist, first responders and other emergency personnel would be particularly vulnerable.

A new invention, however, may help to avert the worst of this worst-case scenario. Aethlon Medical, a small San Diego biotech company, is developing a portable device that removes viruses from blood. Known as the Hemopurifier, it filters not only smallpox but numerous other viruses, including Marburg and Ebola.

The Hemopurifier resembles a shrunken dialysis cartridge, the rolling-pin-size device that purifies the blood of patients whose kidneys have failed. Both use a filter to remove toxins from blood. But unlike traditional dialysis, the Hemo-purifier also includes plant-derived antibodies, such as cyanovirin, that bind to a variety of viruses and eliminates them from the bloodstream. The plant solution can be modified to weed out even genetically engineered germs.

Aethlon has built two versions of its device. One, a foot long and an inch wide, is designed for use in hospitals; the other, the size of a large pen, is meant for use in the field. Both types attach to a pump. But the portable version could work without one, using the patient’s heart as the engine to force blood through the filter [see illustration above].

Aethlon recently shipped several Hemopurifiers to the U.S. Centers for Disease Control and Prevention in Atlanta for cell culture tests on human blood infected with Ebola. Meanwhile the company has already completed its own tests in animals. Though promising, the Hemopurifier still has a few big hurdles to clear, the biggest of which is successful testing in humans. Aethlon is wrapping up safety trials in India and hopes to begin clinical tests in the U.S. by the end of this year.

How To Debug Blood

  1. Infected blood flows into the Hemopurifier through a tube extending from one artery.
  2. The toxin filters work like a colander, allowing small viruses through but not large red and white blood cells. The filter, which is made from a biocompatible plastic called polysulfone, is coated with special plant-derived antibodies that hold fast to the pathogens, ensuring that they don’t reenter the bloodstream.
  3. Purified blood travels back into the body through a second tube inserted into another artery. The human body typically contains about five liters of blood. The entire quantity can flow through the Hemopurifier in about 12 minutes. The process is repeated until all the toxins are removed—usually within a few hours.


TOPICS: Culture/Society; News/Current Events; War on Terror
KEYWORDS: dialyzer; medicine; wot; zaq
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1 posted on 04/09/2006 5:53:22 PM PDT by AntiGuv
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To: PatrickHenry; b_sharp; neutrality; anguish; Fractal Trader; grjr21; bitt; KevinDavis; ...
FutureTechPing!
An emergent technologies list covering biomedical
research, fusion power, nanotech, AI robotics, and
other related fields. FReepmail to join or drop.

2 posted on 04/09/2006 5:54:15 PM PDT by AntiGuv (The 1967 UN Outer Space Treaty is bad for America and bad for humanity - DUMP IT!)
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To: AntiGuv

Gee, as Will Smith said in INDEPENDENCE DAY -- I gotta get me one of those.


3 posted on 04/09/2006 5:55:34 PM PDT by doug from upland (Stopping Hillary should be a FreeRepublic Manhattan Project)
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To: AntiGuv

Can we buy stock?


4 posted on 04/09/2006 5:55:44 PM PDT by WestCoastGal (The President says crank it up June)
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To: WestCoastGal

yes


5 posted on 04/09/2006 5:58:51 PM PDT by Flavius (Qui desiderat pacem, praeparet bellum)
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To: Flavius

Wow. I was always thinking there had to be a way to filter the blood but I was looking at it the wrong way. The way of blocking the redblood and haveing the viruses go through the screen is awesome.

This is going to he hugh!


6 posted on 04/09/2006 6:03:16 PM PDT by BookaT (My cat's breath smells like cat food!)
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To: AntiGuv
Fascinating.

the device consistently removed 55% of HIV from whole human blood within 3 hours

7 posted on 04/09/2006 6:06:14 PM PDT by FReepaholic (I was FReepin' when FReepin' wasn't cool.)
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To: FReepaholic

Interesting..................it was in clinical trials in 2001.....time to get this baby to market.


8 posted on 04/09/2006 6:11:57 PM PDT by MamaLucci (Mutually assured destruction STILL keeps the Clinton administration criminals out of jail.)
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To: MamaLucci; FReepaholic

That is definitely an interesting article. If I might venture a guess based on the dates and the respective information in the articles, this seems to have been first developed solely (or at least primarily) with the intent of treating HIV. What might've happened is that when it was discovered that HIV mostly hides out in the lymphs they realized this wouldn't work for that. However, they switched gears and have been developing it for other blood-borne diseases, especially bioweapon threats.

That's just conjecture on my part, but that would strike me as explaining the five year timespan and the different focus between the 2001 article and this 2006 article.


9 posted on 04/09/2006 6:16:35 PM PDT by AntiGuv (The 1967 UN Outer Space Treaty is bad for America and bad for humanity - DUMP IT!)
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To: AntiGuv
That's cool, as far as it goes...

Two questions:

If one is re-infected (as a primary caregiver in a hospital, for example) how often must one's blood get re-filtered? How infectious is someone after their blood is filtered?

Oh, what is the cost per filter, and how are the filters disposed of?

Nonetheless, looks like good news.

Cheers!

10 posted on 04/09/2006 6:18:24 PM PDT by grey_whiskers (The opinions are solely those of the author and are subject to change without notice.)
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To: WestCoastGal

Yes, a $2 investment in March 04 would be worth $0.75 today.


11 posted on 04/09/2006 6:19:47 PM PDT by Balding_Eagle (REAL men vote Republican)
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To: grey_whiskers

This is interesting, but it won't "cure" you as viruses reproduce within cells. Even if you filter 100% of the viruses from circulating blood, that still leaves a large population of virons within your cells which will reproduce.


12 posted on 04/09/2006 6:20:21 PM PDT by Old_Mil (http://www.constitutionparty.org - Forging a Rebirth of Freedom.)
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To: AntiGuv

Well blow my dress up!!!!!!!!! How cool!!!


13 posted on 04/09/2006 6:21:28 PM PDT by Ditter
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To: AntiGuv

Yes, it sure seems like they switched gears. Still, a very promising development. Thanks for the initial post.


14 posted on 04/09/2006 6:22:42 PM PDT by MamaLucci (Mutually assured destruction STILL keeps the Clinton administration criminals out of jail.)
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To: PatrickHenry

ping


15 posted on 04/09/2006 6:22:47 PM PDT by Wiz
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To: AntiGuv

Great! This is revolutionary!


16 posted on 04/09/2006 6:23:13 PM PDT by Wiz
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To: WestCoastGal

My thoughts too.


17 posted on 04/09/2006 6:25:08 PM PDT by stevio (Red-Blooded Crunchy Con, American Male (NRA))
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To: AntiGuv

They could miniaturize it, implant it and it could be left in indefinitely. That would work, wouldn't it?


18 posted on 04/09/2006 6:27:53 PM PDT by manwiththehands
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To: manwiththehands

Kind of like a stent, huh? Interesting idea! I'm sure they're just focusing on getting to first base for now, but if this succeeds as hoped for then I don't see why that wouldn't be doable, but I am not a doctor.


19 posted on 04/09/2006 6:35:26 PM PDT by AntiGuv (The 1967 UN Outer Space Treaty is bad for America and bad for humanity - DUMP IT!)
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To: AntiGuv

Nice idea, but I doubt it will work. As noted, viruses spread via the blood, but they get into the cells, too.

Also, in a mass epidemic, there's no way something obviously as expensive as this could treat more than a few people.


20 posted on 04/09/2006 6:49:30 PM PDT by Cicero (Marcus Tullius)
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