I guess this means the Federal government can regulate school bake sales. After all, Grandma's apple crisp can affect the national market for baked goods.
Is that a problem if it does? Doesn't seem to be, since Congress is not regulating the interstate commerce of baked goods.
The ONLY time Congress can go into a state and regulate what's going on is if that activity "substantially effects" what Congress is trying to do under their constitutionally assigned powers. And even then, what Congress does IN the states is limited to legislation that is only necessary and proper for them to execute those constitutionally assigned powers. If that doesn't make sense, then you're being intentionally stubborn.
If the Federal Government can regulate growing a half-dozen cannabis plants for personal consumption (not because it is interstate commerce, but because it is inextricably bound up with interstate commerce), then Congress Article I powersas expanded by the Necessary and Proper Clausehave no meaningful limits.
J. Thomas dissenting