.357 is a terrific round, accurate, powerful and flexible - just watch out for overpenetration of your doors and walls. Killing someone else sleeping in the house with a missed shot would ruin your day/week/year/life.
And are known for total throughput of one human target and killing the person behind as well. I have two .357s for SASS shoots (.38 spl loads) but wouldn't chamber .357s for home use. "Make mine a Nine"