There's no way he'll win no matter what kind of guy he is.
No matter what, his wife is in for a battle, and people will want him to focus on her.
It's better for him to sit this time out, and be supportive of his wife.
He can use that the next time he runs.
Reuters used the words "incurable recurrence" but I don't know how accurate that is. I do know that recurrences tend to be very agressive. I will pray for her. In the meanwhile, John should knock it off and take care of his family and get his life in order. He is still very young. And if he really cares about his image, I think he will look very selfish campaigning.
He is a vain egomaniac and she does not tell him off then she is his enabler. Your health comes first. I went through this also.