You need to explain why he/she is wrong. Your post is meaningless otherwise.
I disagree, but I'll play.
1. The cornerstone of evolution is natural selection. There is nothing random about natural selection. It is incorrect to say that evolution is "based solely on randomness."
2. The genetic evidence for evolution is overwhelming. Mitochondrial DNA, for example, mutates at a predictable rate. By counting the number of point mutations in two genomes, we can estimate the date of two species' last shared common ancestor. Amazingly, the dates calculated by this method are almost always identical to the dates generated by morphological analysis and the fossil record. I could get into more genetic evidences for evolution, but this is another completely ridiculous point.
3. The vast majority of mutations are benign. This is a simple factual question where the poster clearly has no idea what he/she is talking about.
4. Again, I don't quite know what the poster is trying to say, so it's a bit hard to refute that statement.