I have a very similar familial history which complicates my decision matrix. Almost all of my known relatives lived into their late 80's and 90's and none of them died of cardio-related problems. I know that my father and likely his father had elevated lipids. Go figure.
With this caution concerning ALS I would be even more reluctent to take them. I already have Dystonia of facial/eye muscles. I sure don't need anything to make that worse. BOTOX does a pretty good job of control. Yes, BOTOX is really used to actually "help" people , not just cosmetic.