Posted on 09/26/2007 10:02:14 AM PDT by Red Badger
Wow!
So, do you just reverse insulin resistance, and you won’t get Alzheimer’s?
Bump!
The researchers had a cure, but after a bowl of ice cream, forgot it.
If that’s true, I wonder whether putting oldsters on a high protein diet would be useful.
If that’s true, I wonder whether putting oldsters on a high protein diet would be useful.
Seems to be a key element. If insulin resistance is a factor, it is possible to reverse the situation................
I wonder if cinnamon, which helps the body use insulin in people prone to Type II diabetes, would be of benefit to people who have Alzheimer’s in the family?
I may start putting cinnamon in my coffee!.............
10 years sooner, and we might have had the Gipper around for a bit longer...
“...could help researchers determine which aspects of existing drugs now used to treat diabetic patients may protect neurons from ADDLs and improve insulin signaling in individuals with Alzheimers.”
Does the research for Alzheimer’s know why these ADDL’s form in the first place?
Mmmmm, I think it's delicious! But I - no pun initially intended - sometimes forget to dash some in, unless I'm at a Starbuck's or coffee shop.
OK, we have known about the Amyloid protein buildup associated with Alzheimer’s and other diseases for a decade or more. This paper shows the ADDLs interfere with migration of insulin receptors to dendritic regions where they must normally function. The root problem is the amyloid protein interference with the functional insulin receptors. It seems that treatment objective is still to reduce the amyloid deposits, which seems very unlikely, or more appropriately to prevent the ADDL deposition in the first place. I still don’t see a break-through in treatment or prevention of this dreaded disease. This paper is more about functional interference with insulin receptors associated with memory. This is just one more functional alteration associated with excessive amyloid deposition.
I’m sure this is just one piece of the overall puzzle. But it may point another researcher in the right direction.................
Agreed. So it’s hard to know whether or not standard diabetic treatments would be of any help. But I’m thinking that any treatment that decreases insulin resistance may be of help when we’re still in the pre-Alzheimer’s pre-diabetic phase...
bmflr
There is no pre-treatment, but there is prevention. If it comes in a box or a bag, don’t eat it. Too many people today eat like cattle in a feedlot, and what do they eat? grain, and lots of it, including refined carbs and way too much sugar. Reduce grain consumption to 20% of today’s average human diet and most of these diseases will go away.
Thanks to MainFrame65 for the alert.
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