Posted on 10/30/2007, 1:30:25 PM by decimon
Research in the FASEB Journal lays the groundwork for safe, new cancer therapy
The next cancer drug might come straight from the grocery store, according to new research published in the November 2007 issue of The FASEB Journal. In the study, French scientists describe how high and low doses of polyphenols have different effects. Most notably, they found that very high doses of antioxidant polyphenols shut down and prevent cancerous tumors by cutting off the formation of new blood vessels needed for tumor growth. Polyphenols are commonly found in red wine, fruits, vegetables, and green tea.
At relatively low doses, the French researchers found that the same polyphenols play a beneficial role for those with diseased hearts and circulatory systems by facilitating blood vessel growth. The amount of polyphenols necessary for this effect was found to be the equivalent of only one glass of red wine per day or simply sticking to a healthy diet of fruits and vegetables containing polyphenols. This diet is known as the “Mediterranean Diet.” This study also adds to a growing body of research showing dose-dependent relationships for many types of commonly used compounds. For instance, research published in the October 2006 issue of The FASEB Journal shows that aspirin, through different mechanisms, also has a dose-dependent relationship for heart disease and cancer.
"When it comes to finding treatments for complex diseases, the answers are sometimes right there waiting to be discovered in unexpected places like the produce aisles and wine racks of the nearest store,” said Gerald Weissmann, M.D., Editor-in-Chief of The FASEB Journal. “But it takes modern science to isolate the pure compound, test it in the lab, and to go on from there to find new agents to fight disease.”
According to the authors, the amount of polyphenols necessary to obtain an anti-cancer effect is the equivalent of drinking about a bottle of red wine each day. This amount of daily alcohol consumption obviously is unhealthy, but the research suggests that polyphenols extracted from plants or red wine could be converted into a pill that is highly likely to be safe. Such a pill also would be relatively easy and inexpensive to create and deliver.
“The use of plant polyphenols as therapeutic tools presents important advantages,” said Daniel Henrion, senior author of the study, “because they have a good safety profile, a low cost and they can be obtained everywhere on the planet.”
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The FASEB Journal (www.fasebj.org) is published by the Federation of American Societies for Experimental Biology (FASEB) and is consistently ranked among the top three biology journals worldwide by the Institute for Scientific Information. FASEB comprises 21 nonprofit societies with more than 80,000 members, making it the largest coalition of biomedical research associations in the United States. FASEB advances biological science through collaborative advocacy for research policies that promote scientific progress and education and lead to improvements in human health.
"A bottle a day cures cancer" they proclaim!
Stuff like this is why they invented the FDA (Food and Drug Administration).
Now for some lengthy testing.
I volenteer.
Hopefully Tomatoes have a lot, with the amount of Pasta I eat, hopefully it makes a difference.
I know I always feel better after a couple glasses of wine.
I’ll volunteer
Not really. They say the requisite amount from wine is impractical but the polyphenols in pill form is viable.
If you don't mind looking like Sydney Greenstreet then that could be a good program to follow.
There are many chemicals that will kill cancer in a test tube. Until they actually succeed in human trials, this article is just advertising hype for the wine industry.
Polly Feenman filled five pill bottles with polyphenols in pill form.
En Vino Veri Tas.
The Park Bench Diet
This article fails to mention that cocoa also contains polyphenols, and even better compounds that prevent cancer and also strengthen blood vessels, helping to prevent strokes, heart attacks and aneurysms.
The Italians eat Nutella on their bread in the morning(I think that’s the correct spelling). I have been using this lovely chocolate spread for years. I also drink a glass red wine at lunch then 1 or 2 again at dinner.
Fabulous!
...and my wife goes, “eeewwwww” when I dip my Oreo in my cabernet. Hah! I was just ahead of my time!
Too bad for me, because I despise tomatoes in pretty much any form.
“Polyphenols are commonly found in red wine, fruits, vegetables, and green tea.”
All part of my daily regimen. Here’s hoping!
Perhaps the best source available in health stores is quercetin. It is usually sold in combination with Vitamin C.
My son LOVES NUTELLA. Agree completely.
You can get the same amount of polyphenols from drinking grape juice without the benefits/hazards of consuming the alcohol. Blackberry juice is even better.
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