I’d suggest a 12/16 guage pump shotgun with buckshot. It will have the range to take out the coyote and not carry like a rifle. Also makes good home defense, which is a significant issue.
12 gauge 00 buck would be OK for coyotes at short range, under 25-30 yards or so, but the shot pattern spreads too fast in most guns to be reliable beyond that distance. I don't know about CA coyotes, but around here (north GA) if you can get within 100 yards of one you are either very lucky or an expert stalker in the same class with Daniel Boone and Davy Crockett. Coyotes are tough critters, and if you just wound him he will run off and then you don't know it he dies or not. A coyote gutshot with a .22 rimfire or a buckshot pellet will travel for miles before going down and dying in misery a few days later, and I won't do that to any animal if I can help it.
I don't have a coyote problem out here where I live, not yet anyway. But if I did I think I would buy a Savage model 110 bolt action rifle with a 3-9x scope, probably a .243 caliber like the one my neighbor uses for deer hunting. With a 100 grain bullet his rifle will make a clean kill on a buck deer at 200 yards or more, and I'm sure it would work even better on a 50 lb coyote. Of course it also would do double duty as a fine deer rifle if I bought one, and you can't say that for any .22 centerfire round even though some folks around here use those for deer.
I used to hunt deer in the thick woods down in FL's Big Cypress Swamp with my 90+ year old model 94 Winchester .30-30 with a 26" octagon barrel, and I'm sure it would kill a coyote like a lightning bolt. But now that Winchester is out of business it's become a collector's item in NRA very good original condition, and I don't want to destroy it's collector value by drilling and tapping it for a scope mount.