a CZ does fit the hand VERY nicely.
But for some FUN home defense how about one of these.
http://calicolightweaponsystems.com/home/
Watch the vid on the fron page.
There is a developer who has made a handy carbine in .45 ACP that has almost zero recoil and allows the shooter to stay on target even with full auto fire. I can’t remember the name, thoyugh.