Posted on 12/18/2007 11:11:23 PM PST by GodGunsGuts
Then why have you attributed this to the obviously impossible 'mutation,' rather than the transfer of preprogrammed info from one segment of the code to another?
Our creator knew from the beginning the conditions to which we, and all other life, would need to adapt, and provided the necessary response deep in our DNA on the day of creation.
Why not attribute this difference in Amino Acid sequence to a difference in DNA sequence? It is predictable what change will result in what new amino acid sequence according to the code, the actual code, the code of molecular genetics.
UUU Phenylalanine (Phe)
UCU Serine (Ser)
UAU Tyrosine (Tyr)
UGU Cysteine (Cys)
UUC Phe
UCC Ser
UAC Tyr
UGC Cys
UUA Leucine (Leu)
UCA Ser
UAA STOP
UGA STOP
UUG Leu
UCG Ser
UAG STOP
UGG Tryptophan (Trp)
CUU Leucine (Leu)
CCU Proline (Pro)
CAU Histidine (His)
CGU Arginine (Arg)
CUC Leu
CCC Pro
CAC His
CGC Arg
CUA Leu
CCA Pro
CAA Glutamine (Gln)
CGA Arg
CUG Leu
CCG Pro
CAG Gln
CGG Arg
AUU Isoleucine (Ile)
ACU Threonine (Thr)
AAU Asparagine (Asn)
AGU Serine (Ser)
AUC Ile
ACC Thr
AAC Asn
AGC Ser
AUA Ile
ACA Thr
AAA Lysine (Lys)
AGA Arginine (Arg)
AUG Methionine (Met)START
ACG Thr
AAG Lys
AGG Arg
GUU Valine Val
GCU Alanine (Ala)
GAU Aspartic acid (Asp)
GGU Glycine (Gly)
GUC (Val)
GCC Ala
GAC Asp
GGC Gly
GUA Val
GCA Ala
GAA Glutamic acid (Glu)
GGA Gly
GUG Val
GCG Ala
GAG Glu
GGG Gly
bookmark for later reading
You’re simply confused.
You’re misapplying the term ‘mutation’ in accordance with the smoke screen agenda of the evo gang. Mutation is an accidental event, that destroys a portion of code, and usually results in the death of the organism. Even if death is not the result, neither is a positive outcome. Changes that are due to a response from information already contained in the code to an environmental change are not ‘mutation.’
The response of bacteria to antibotics or other agents is an example. The info that allows some of the bacteria to survive, while others perish, is already there, but is dominant in only a portion of the population. The continued breeding of the strain that results, by continuing the use of the antibiotic, is not mutation, but selective breeding, much like has been done with pets and livestock. All of these populations have demonstrated the ability to gravitate back when interbreeding occurs, and bacteria will do the same if the antibiotic is discontinued.
No mutation, just the expected statistical distributions prevailing.
==Those are all levels of control that someone could claim was a ‘code within a code’ or a ‘code upon a code’ but really there is just one code and many many multiple levels of control.
It would appear that you are at odds with the entire field of epigenetics. There are indeed codes upon codes—GGG
“Sensors and signals: a coactivator/corepressor/epigenetic code for integrating signal-dependent programs of transcriptional response”
http://www.genesdev.org/cgi/content/full/20/11/1405
These dynamic, “histone code”-driven interactions can represent the sequential order of step-to-step transitions during transcriptional initiation.
http://www.genesdev.org/cgi/content/full/20/11/1405
“From recent work, it is becoming increasingly clear that these modifications form a histone code that regulates chromatin function through their ability to recruit specific interacting proteins that recognize a single or combinatorial set of modifications(Strahl and Allis 2000; Turner 2000; Jenuwein and Allis 2001).”
http://www.genesdev.org/cgi/reprint/17/5/654.pdf
Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly.
[My paper] J Nakayama , J C Rice , B D Strahl , C D Allis , S I Grewal
“The assembly of higher order chromatin structures has been linked to the covalent modifications of histone tails. We provide in vivo evidence that lysine 9 of histone H3 (H3 Lys9) is preferentially methylated by the Clr4 protein at heterochromatin-associated regions in fission yeast. Both the conserved chromo- and SET domains of Clr4 are required for H3 Lys9 methylation in vivo. Localization of Swi6, a homolog of Drosophila HP1, to heterochomatic regions is dependent on H3 Lys9 methylation. Moreover, an H3-specific deacetylase Clr3 and a beta-propeller domain protein Rik1 are required for H3 Lys9 methylation by Clr4 and Swi6 localization. These data define a conserved pathway wherein sequential histone modifications establish a “histone code” essential for the epigenetic inheritance of heterochromatin assembly.”
http://lib.bioinfo.pl/pmid:11283354
“We interpret these modifications in light of previously published data and propose a new and testable model for how cells implement the histone code by modulating nucleosome dynamics.”
http://www.ncbi.nlm.nih.gov/pubmed/15523479
“These findings assign a biological function to this amino acid and highlight a gene type–specific requirement for a residue within the CTD heptapeptide, supporting the existence of a CTD code.”
http://www.cipsm.de/en/publications/researchAreaD/index.html?style=0
OLD DOGS, NEW TRICKS
“S. Grewal (Cold Spring Harbor, NY) presented an elegant combination of genetics and biochemistry that focused on how modifications of the histone tails regulate one another in the establishment of heterochromatin in fission yeast. Grewal showed that deacetylation of lysine 14 (K14) on histone H3 is required for the subsequent methylation of K9, which in turn recruits Swi6, the Schizosaccharomyces pombe equivalent of HP1. The elucidation of this epigenetic pathway not only defines the sequence of events that establish heterochromatin, but also establishes a revolutionary ‘histone code’ (Nakayama et al., 2001), in which modifications of the histone tails carry information for the regulation of gene expression.”
http://www.nature.com/embor/journal/v3/n3/full/embor204.html
Translating the histone code.
Jenuwein T, Allis CD.
Research Institute of Molecular Pathology (IMP) at the Vienna Biocenter, Dr. Bohrgasse 7, A-1030 Vienna, Austria. jenuwein@nt.imp.univie.ac.at
“Chromatin, the physiological template of all eukaryotic genetic information, is subject to a diverse array of posttranslational modifications that largely impinge on histone amino termini, thereby regulating access to the underlying DNA. Distinct histone amino-terminal modifications can generate synergistic or antagonistic interaction affinities for chromatin-associated proteins, which in turn dictate dynamic transitions between transcriptionally active or transcriptionally silent chromatin states. The combinatorial nature of histone amino-terminal modifications thus reveals a “histone code” that considerably extends the information potential of the genetic code. We propose that this epigenetic marking system represents a fundamental regulatory mechanism that has an impact on most, if not all, chromatin-templated processes, with far-reaching consequences for cell fate decisions and both normal and pathological development.”
http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=11498575
“Gene transcription occurs on a nucleosomal template known as chromatin. The recruitment of the transcriptional regulators and the transcription machinery to promoter chromatin is coordinated by a genetic code on the DNA and an epigenetic code on the histone proteins.”
Phosporylation of RNA polymerase is not even THAT much of a code, it is just fluffy langauage that has you all confused. Like editor-surveyor (how would I ping him to this post) are you looking for some sort of “Bible code” of information ‘hidden deep within the DNA’?
And, recent rsearch indicating that
what we think about intensely, a lot, long term
CAN ALTER OUR VERY DNA
Gives new meaning to the Scripture
AS A MAN THINKS IN HIS HEART, SO IS HE.
They are in the process of attempting to decode what your fellow Evos describe as a code. Didn’t you read the links I sent you?
Do you have a link for that research. I am VERY interested. Thanks—GGG
Sorry, I don’t.
IIRC, I read it on FR.
Would appreciate a link, myself, for my students.
If I find one, I’ll post it to this thread. But I have a lot of other higher priorities first.
Probably won’t even get around to looking for a link.
Sorry.
That’s ok. I’ll find it. I have also stumbled on to similar studies in which epigenetic responses to environmental conditions can be passed on to offspring. If your interested, I’d be glad to send them to you when I get around to tracking them down.
All the best—GGG
To return to the car analogy, I may not know what all the parts do, but I know it is an internal combustion engine that I pour gas into and get spinning tires. You seem to be trying to say that these ‘new codes’ are like a electric engine that kicks in on the car; but the only thing making this particular car go is the internal combustion engine. The carburetor controls how the engine burns gas, but it doens’t make the car go forward. DNA methylation and RNA Polymerase phosporylation are all important control mechanisms to modulate the functioning of the genome, but the function of the genome is to code for proteins that perform a molecular task.
PS I’m for Hunter in 08 too. At least we have that in common!
Let’s work out this debate thing first, and then we can return to codes upon codes.
Sure. would be blessed to have such.
Here’s one. Read the second half especially. Fascinating stuff.
https://notes.utk.edu/bio/greenberg.nsf/0/b360905554fdb7d985256ec5006a7755?OpenDocument
What happened to the debate re: AIDS? Creation vs. Evolution? Etc? You have suddenly gone silent. What gives?
Which means you are not at all confident in your point of view and depend on force to uphold the same. So much for being willing to let the evidence lead where it may.
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