Yup. When my doctor recently doubled my cholesterol medicine, I quit taking it completely.
My dad was taking Lipitor, and had very bad effects from it in the area of cognitive abilities. I did some reading up on it; after a physical at my Doc, one of his assistants called me and was ready to write me a script for Lipitor.
I flatly refused. I think my exact words were: "no way in hell".
Quite frankly, I feel fine. I still eat, drink and smoke what I want, when I want. If I keel over with a massive heart attack tomorrow, so be it. I'd rather go quick than slowly fade away, and be put into some aging warehouse like most people these days. If it ever comes down to that; my family has standing orders: give me a gun.