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Strep bacteria may treat pancreatic cancer
Yahoo News ^ | Fri Apr 18, 3:46 PM ET | David Douglas

Posted on 04/21/2008 8:17:25 AM PDT by null and void

NEW YORK (Reuters Health) - In mice implanted with human pancreatic cancer tumors, injecting live Streptococcus bacteria, similar to those that cause strep throat, directly into the tumors caused the tumors to shrink and die, German scientists report.

"The utilization of live bacteria," as a danger signal, Dr. Claudia Maletzki told Reuters Health, "obviously has great potential for activating the immune system."

Given the poor prognosis of patients with advanced pancreatic cancer, "novel" interventions are "imperative," Maletzki and colleagues at the University of Rostock note.

In culture experiments, the researchers established that streptococcal bacterium known as S. pyogenes could mediate severe injury to pancreatic cancer cells.

The team went on to examine the efficacy of S. pyogenes in a mouse model of aggressive pancreatic cancer known to have an intrinsic insensitivity to existing anti-cancer agents.

They found that a single application of the live bacteria resulted in complete regression or death of the pancreatic tumors.

In addition to direct destructive activity, they observed a helpful tumor-specific immune response, with generation of tumor-specific cells.

"We think that patients suffering from tumors with very bad prognosis could substantially benefit from such alternative treatments stimulating the immune system," Maletzki said.


TOPICS: Culture/Society
KEYWORDS: health; pancreas; pancreaticcancer
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1 posted on 04/21/2008 8:17:26 AM PDT by null and void
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To: null and void

Patrick Swayze, call your office ...


2 posted on 04/21/2008 8:18:50 AM PDT by sono (The real threat we face in this country is Liberalism.)
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To: null and void

If this really works, this guy deserves the Nobel Prize....


3 posted on 04/21/2008 8:20:10 AM PDT by Sleeping Freeper
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To: CholeraJoe

-amazingly simple. Hope it really works.


4 posted on 04/21/2008 8:22:15 AM PDT by tioga
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To: null and void

Neat! Thanks, Nully!


5 posted on 04/21/2008 8:23:15 AM PDT by Smokin' Joe (How often God must weep at humans' folly.)
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To: tioga

Like most quack, sensationalist reports, I doubt this one will pan out.


6 posted on 04/21/2008 8:24:16 AM PDT by CholeraJoe (Shaking in the flatlands. "All your Richter scale are belong to us.")
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To: Sleeping Freeper
"...If this really works, this guy deserves the Nobel Prize...."

Or more. I wonder what other kinds of tumours the bacteria could kill.....this could be something very big.

7 posted on 04/21/2008 8:24:33 AM PDT by Victor (If an expert says it can't be done, get another expert." -David Ben-Gurion, the first Prime Minister)
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To: sono

I bet he might be willing to be used as a test subject.


8 posted on 04/21/2008 8:24:54 AM PDT by AxelPaulsenJr (God Bless George W. Bush)
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To: CholeraJoe
"...Like most quack, sensationalist reports, I doubt this one will pan out....."

I would normally agree with you. But this is being reported by a major news organization, Reuters.

The "quack" stuff is for supermarket tabloids.

9 posted on 04/21/2008 8:26:58 AM PDT by Victor (If an expert says it can't be done, get another expert." -David Ben-Gurion, the first Prime Minister)
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To: sono

Is pancreatic cancer the kind he has?......


10 posted on 04/21/2008 8:27:16 AM PDT by Red Badger ( We don't have science, but we do have consensus.......)
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To: CholeraJoe

it’s got to be a quack who invented the colonoscopy......


11 posted on 04/21/2008 8:29:00 AM PDT by tioga
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To: CholeraJoe

http://lib.bioinfo.pl/auid:7761222


12 posted on 04/21/2008 8:29:10 AM PDT by Red Badger ( We don't have science, but we do have consensus.......)
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To: Victor
But this is being reported by a major news organization, Reuters.

Reuters? Were there any pictures with the article?

13 posted on 04/21/2008 8:29:25 AM PDT by glorgau
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To: tioga
it’s got to be a quack who invented the colonoscopy......

HAving had one and polyps removed, I am grateful for that "quack".............

14 posted on 04/21/2008 8:30:28 AM PDT by Red Badger ( We don't have science, but we do have consensus.......)
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To: Red Badger

I’ll let you know by the end of the week what I “think”.......(sigh)


15 posted on 04/21/2008 8:36:57 AM PDT by tioga
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To: sono

This type cancer is a death sentence. I hope this is true.


16 posted on 04/21/2008 8:37:14 AM PDT by stravinskyrules (Why is it that whenever I hear a piece of music I don't like, it's always by Villa-Lobos?)
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To: tioga

Don’t sweat it. They give you a “happy shot”, you go to sleep and wake up an hour or so later and you don’t know a thing.......


17 posted on 04/21/2008 8:39:35 AM PDT by Red Badger ( We don't have science, but we do have consensus.......)
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To: Red Badger

it’s the “senna” tablets that have me worried! LOL


18 posted on 04/21/2008 8:41:23 AM PDT by tioga
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To: tioga

Senna tablets? I had to drink a gallon of cherry flavored propylene glycol the night before to clean out the system. It’s a cousin to anti-freeze, but not poisonous like it (ethylene glycol). It’s thick and sweet and clear......


19 posted on 04/21/2008 8:43:59 AM PDT by Red Badger ( We don't have science, but we do have consensus.......)
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To: Red Badger

did that the first time, years ago.......this time it’s a truckload of senna tablets the day before.....what a way to lose a few pounds...


20 posted on 04/21/2008 8:45:53 AM PDT by tioga
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