It will be a reverse "you're-no-Jack-Kennedy" thing. Biden will begin by questioning her experience. She then needs to go on offense, telling him HE's the inexperienced one, that HE has never overseen a budget for a state of 600,000 people, that HE has never had to fire people, that HE has never had to resist the full power of the feds trying to 'give away" a bridge to nowhere; and that HE isn't the commander in chief of a national guard that just happens to patrol the border with Russia, who at present has not been acting much like an ally (she'll have to be careful not to call them an "enemy" or "dangerous.")
In short, in a few sentences she can elevate herself to FAR more experience than the entire Dem ticket (and McCain too, although I doubt Biden would mention that).