And how are you going to demonstrate that mutation is non random when every experiment with error prone DNA polymerase or mutatagens show that mutations create unique genetic variation rather than making the same mutations every time?
That's not what real scientists are finding:
http://www.ncbi.nlm.nih.gov/pubmed/9926936
"Mutation hotspots were identified by comparing the observed distribution of mutations to the pattern expected from a random multinomial distribution."..."Both high evolutionary constraint and mutation hotspots are noted at amino acids close to the protein-DNA interface and at others more distant from DNA, often buried within the core of the folded protein but sometimes on its surface."
Oops, not random...