[RegulatorCountry]

The “off label” use of Benadryl, as well as other inhibitors of histamine resonse, has been noted as useful with mast cell tumors in veterinary medicine, with dogs. Not aware of any human studies.

[hennie pennie]

Thanks for this interesting information. I am unable to take benedryl by mouth, as I will fall asleep for about 48 hours, and then remain very groggy for several days thereafter. Before I started using a neti pot, occasionally my sinuses became so inflamed that sometimes at bedtime, I would rub benedryl cream into my forehead, then take a very hot bath - and somehow this did seem to relieve the sinus pressure & pain without knocking me out for days, although I would still get pretty groggy.

I’ll have to get over to google and find out what mast cell tumors are, sometime today!

Thanks again.