Getting the bill out of the Senate is a prerequisite of requesting a conference. The GOP can object to passage of the bill, and/or any amendment. Each persistent objection results in a 60 vote threshold to move ahead.
If the bill gets to Conference, the "take it up, amend it, pass it again" routine must be repeated until both chambers agree on exactly the same language.
You do realize, of course, that all the rhetoric and speeches are for show only, and this takeover cannot be stopped simply due to the numbers?