Large numbers of multi- role fighters are called a target rich environment by the fighter jocks. Producing F-22s in larger numbers will have an exponentially better effect on our pilots kill ratios not to mention their survivability.
Multi basing modes and multi-service use make the F-35 user friendly for spare parts. That doesn't give the F-35 superior airworthiness or survivability.
FYI I built F-16s for General Dynamics before they became Lockheed Martin. Yes they know what they are doing. Building an aircraft that their customer specifies.
The F-22 and F-35 won't be facing each other in combat. Comparing what they do an how that perform in that respect....it doesn't make much sense. I look at it this way: Our previous air superiority fighter, the F-15 whipped its comtemporaries. While the F-16 and -18 (originally the -17) were developed as LWFs, they transistioned well into the multi-role niche and could still take their adversaries in the air to air arena.
Considering we took aircraft originally designed for air combat and made them successful in other areas, I am confident we've learned a thing or two and will make a fine true multi-role fifth generation model. If Lockheed/Martin brings us another multi-role aircraft as "poor" as either the -16 or -18, I think we'll be just fine.