Posted on 05/25/2011 2:10:48 PM PDT by neverdem
Human proteins with affinity for dermatan sulfate have the propensity to become autoantigens.
immunology ping
Thye are a suspicious bunch. Never trusted them. Figures a rogue GAG would make all that trouble.
Thank you!
Thanks for the interesting post. I have alopicia, and the doctor has told me that it’s a typr of auto-immune disorder. I wonder if this research will benefit me.
I autoimmuned an ex wife once
An alternate hypothesis would be:
iron loading in the liver reduces HCl secretions in the stomach and eventually in the gut. Deficient HCl in the gut
causes incomplete digestion, huge proteins that resemble pathogens, massive over-growths of alien flora in the gut and absorption of huge proteins into the blood that are mis-identified as pathogens. The immune response would stay on high alert 24/7/365 while attacking the huge food proteins.
The iron in the liver reduces the levels of hydroxylated vitamin d which upregulates the autoimmune pathology.
I hope this research will prove fruitful. I suffer from a few auto-immune disorders. Usually when you have one you get more. They tend to cluster. Sadly.
I like yours better. Enough vitamin D seems to reduce a lot of autoimmune activity, and avoiding grains makes the gut flora more beneficial as well as keeping these large proteins from slipping into the bloodstream. I am going with your hypothesis.
I have at least one auto-immune disease as well, they are testing me for a couple of others as whatever it is, is flaring up with a vengence right now.
I feel like I should be able to understand this, but I don’t. :(
I have been very busy and have not taken time to look into an anti-inflammation diet, but most autoimmune disease have some kind of inflammatory element to them.
I don’t much either, really! All I know is that since we started supplementing with vitamin D around here, no one seems to get sick. Including the little autoimmune things. We don’t have a big autoimmune thing here, thank G-d, but I one of us did, I’d add testing and supplementation of D.
And when you eat grains, especially glutens, they are so hard to digest and they mess up the digestion process in your gut, which takes place because of the gut bacteria, the GOOD ones. Also, when you are eating grains, big particles can get through some of the intestinal holes and these proteins get into your bloodstream and can make you sick or give you neurological problems. Avoiding grains is a very healthy thing to do. Many of the digestive disorders like celiac, IBF, and Crohn’s can be avoided by avoiding glutens or (better) all grains.
Well the two things that have seemed to help me the most have been vitamin D (and B complex) and not eating any wheat. I have been doing that for about a year now. I am not 100% but I would say I am at least 70% better. Enough better that I wouldn’t change back and my Doctor wants me to continue.
I have an inflammatory myopathy.
I’m so sorry for your loss.
So sorry to hear of your husband’s passing. Praying right now for God’s sustaining grace and comfort for you.
I am really sorry to hear that. My condolences.
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