http://wwwnc.cdc.gov/eid/article/8/4/01-0175_article.htm
Thanks....found a good article on CDC website. Some of the material you quote appears to come from this paper.
Learn something new everyday.
Disease was doing the job all along and it's fairly easy to see that it had happened repeatedly in this part of the world.
It was probably the reason their technological advances were behind that of the rest of the world ~ even though their agriculture was ahead ~ I could write a case for small, isolated agricultural technologists being able to conduct long term breeding experiments denied to those living in centrally administered empires.