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Airway Abnormality Discovered in Children With Autism
http://www.clinicalpsychiatrynews.com ^ | By: DOUG BRUNK, Clinical Psychiatry News Digital Network

Posted on 11/01/2011 7:53:17 AM PDT by Red Badger

The presence of extra bronchial passageways in children may be a marker for autism and autism spectrum disorders, results from a novel study demonstrated.

"Autism continues to remain underdiagnosed or missed altogether, unrecognized and undiagnosed because appropriate tools for screening for autism have not been available," lead investigator Dr. Barbara A. Stewart said during an interview in advance of the annual meeting of the American College of Chest Physicians, where the study was presented. "Until now, there has been no objective evidence for autism spectrum disorder."

Dr. Stewart of Nemours Children’s Clinic in Pensacola, Fla., conducted bronchoscopic evaluations in 49 children younger than age 18 years who had autism or autism spectrum disorder and were seen in a pulmonary clinic with a diagnosis of cough that was unresponsive to therapy. She noticed that although the airways of the children initially appeared normal, the lower airway had doubled branches, or "doublets" as she calls them.

"Another way to think of this is systematic doubling of airways in the lower airways," Dr. Stewart explained. "When airways divide beyond the first generation, they typically branch like a tree, with one branch on one side and one on the other. A doublet occurs when there are twin branches that come off together instead of one, which are exactly symmetrical, in each of the lower locations that can be seen."

Because of a lack of uniformity in nomenclature in the medical literature, Dr. Stewart said that it’s difficult to determine if doublets have been previously identified, let alone studied. "There are no known studies in the literature attempting to define or even speculate on a function, purpose, role, [or] significance of the ‘double take-off’ airway anomaly," she said.

She speculated that children with doublets may have higher airway resistance, which "might be why the population of children with autism spectrum disorder are not truly athletic people."

Although the potential association between autism and airway structure is intriguing, Dr. Stewart emphasized the preliminary nature of the findings. "That there is such a compelling correlation between a perplexing bronchial anomaly and a seemingly unrelated condition such as autism begs further study," she said. "This discovery needs to be validated by much larger–scale investigations than my own."

She went on to note that research into neurodevelopmental processes, including autism and autism spectrum disorder, and anatomical anomalies such as doublets in the bronchi "should and will be accelerated." She also expressed the hope that "likely less-invasive alternatives to bronchoscopy will be discovered in the near future to justify identification of airway anomalies as a diagnostic tool for autism."

Dr. Stewart said that she had no relevant financial conflicts to disclose.


TOPICS: Business/Economy; Culture/Society; US: Florida
KEYWORDS: autism; discovery; health

Dr. Barbara Stewart

1 posted on 11/01/2011 7:53:22 AM PDT by Red Badger
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To: Red Badger

Does any FReeper have an autism ping list?............


2 posted on 11/01/2011 7:55:01 AM PDT by Red Badger (Obama's number one economics advisor must be a Magic Eight Ball.................)
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To: Red Badger
The presence of extra bronchial passageways in children may be a marker for autism and autism spectrum disorders, results from a novel study demonstrated.

Wow. Who'da thunk that Thiomersal in vaccines could cause extra bronchial passageways to develop!!!
3 posted on 11/01/2011 7:58:36 AM PDT by aruanan
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To: Red Badger

Interesting theory...I wonder if my Asperger’s child (and possibly myself) have such a feature...


4 posted on 11/01/2011 7:59:09 AM PDT by JRios1968 (I'm guttery and trashy, with a hint of lemon. - Laz)
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To: Red Badger

Color me cynical. But here comes another medical reason to abort a “defective fetus.”


5 posted on 11/01/2011 8:11:34 AM PDT by Truth is a Weapon (Truth, it hurts so good.)
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To: Red Badger; All
My wife and I have adopted two autistic children, and one with Down syndrome who may also be autistic. While none of them are what one might call 'truly athletic," none of them have persistent coughs or activity intolerance. Our daughter with Down syndrome has a "floppy airway," but that's attributable to DS and not autism.

As a researcher (as every nurse should be), I deduce that Dr. Stewart's survey population was "cherry-picked" in order to create a basis for her problem statement. This is handy for creating basis for a problem statement, but 49 children out of a population of tens of thousands is not a representative number by any stretch of the imagination.

There are certain terms and phrases in Dr. Stewart's article that raise the red flags of eugenics. I'd be interested to see her writeup of the full, finished project- unless this is all the work she intended to do in the first place.

6 posted on 11/01/2011 8:39:35 AM PDT by 60Gunner (Eternal vigilance or eternal rest. Make your choice.)
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To: aruanan

I’m not sure this makes a lot of sense. Wouldn’t then all autism babies exhibit signs of autism from birth. Why do some only start exhibiting symptoms at around 18 months?

I read an article yesterday that stated that the CDC had essentially ignored evidence from Denmark that their autism rates fell when they removed mercury from their vaccines.

I’m not sure we’ll get the whole story from either side.


7 posted on 11/01/2011 8:50:39 AM PDT by Roos_Girl (The world is full of educated derelicts. - Calvin Coolidge)
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To: Red Badger

When I was in school they taught us that abnormalities come in 3’s ..so this is not surprising..


8 posted on 11/01/2011 9:04:01 AM PDT by RnMomof7
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To: JRios1968

I’ve noticed since I was growing up, I was always getting winded while playing sports. It included even today when I’m in martial arts class. I’m always getting winded.


9 posted on 11/01/2011 9:46:58 AM PDT by NorthStarStateConservative (Springtime in America will arrive on January 21, 2013.)
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To: JRios1968

I’ve noticed since I was growing up, I was always getting winded while playing sports. Even today when I’m in martial arts class. I’m always getting winded.


10 posted on 11/01/2011 9:47:12 AM PDT by NorthStarStateConservative (Springtime in America will arrive on January 21, 2013.)
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To: NorthStarStateConservative
I’ve noticed since I was growing up, I was always getting winded while playing sports. It included even today when I’m in martial arts class. I’m always getting winded.

Same here!

11 posted on 11/01/2011 10:03:55 AM PDT by JRios1968 (I'm guttery and trashy, with a hint of lemon. - Laz)
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To: Red Badger
conducted bronchoscopic evaluations in 49 children younger than age 18 years who had autism or autism spectrum disorder and were seen in a pulmonary clinic with a diagnosis of cough that was unresponsive to therapy.

That's an awfully specific sampling.
12 posted on 11/01/2011 10:07:32 AM PDT by Ellendra ("It's astounding how often people mistake their own stupidity for a lack of fairness." --Thunt)
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To: JRios1968

Heh. I just overcame it by just training harder than everybody else. Even to this day, where I do MAs more as a hobby than something serious, I’m always training my hardest. Stadium steps, 10 mile bike rides, racketball drills, etc.


13 posted on 11/01/2011 10:29:09 AM PDT by NorthStarStateConservative (Springtime in America will arrive on January 21, 2013.)
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To: NorthStarStateConservative

That’s what I need to do...except I am really getting in years (silly excuse, I know)


14 posted on 11/01/2011 10:53:27 AM PDT by JRios1968 (I'm guttery and trashy, with a hint of lemon. - Laz)
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To: Roos_Girl
A caller on CoastToCoastAM offered another angle on the mercury/autism issue. His theory is that the autistic individuals have a genetic predisposition to autism that is triggered by the presence of mercury. It takes both the sensitivity and the triggering agent to cause the expression of the problem. If it was mercury alone, everyone exposed would become autistic and removing mercury would completely eliminate the problem. Autism is a multi-faceted problem. I think there are many triggering agents and varying degrees of sensitivity based on genetic heritage.
15 posted on 11/01/2011 11:40:43 AM PDT by Myrddin
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To: Myrddin

Agreed. There was also a separate article that told of two different reasons for autism; one in the brain and one in the gut. Say a young baby is given antibiotics for some reason, that could trigger a problem. Or the other side of the coin, the baby is given a series of vaccines and the mercury affects him. I think both antibiotics and vaccines are overused.

Vaccines can be made without mercury, so why not just do it? I’m not necessarily anti-vaccine, but the number of them just keep going up up up and I just don’t see the benefit of a baby getting a Hep B vaccine, for instance, when for all intents and purposes Hep B is a sexually transmitted disease versus the possible side effects.


16 posted on 11/01/2011 12:27:11 PM PDT by Roos_Girl (The world is full of educated derelicts. - Calvin Coolidge)
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To: Myrddin

Interesting theory. Except they haven’t been using mercury in vaccinations for a decade and (detected) autism rates are still rising.


17 posted on 11/01/2011 12:36:04 PM PDT by kevkrom (This space for rent.)
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To: Roos_Girl
I read an article yesterday that stated that the CDC had essentially ignored evidence from Denmark that their autism rates fell when they removed mercury from their vaccines.

Probably had good reason to ignore it considering that Denmark’s MMR/mercury & autism researcher Poul Thorsen 49, is going to be extradited "on 13 counts of wire fraud and nine counts of money laundering. This relates to monies paid to Thorsen by the US Centers for Disease Control including for research into the relationship between autism and exposure to vaccines. Thorsen used the stolen money to buy a home in Atlanta, a Harley Davidson motorcycle and two cars, prosecutors said."
18 posted on 11/01/2011 2:43:26 PM PDT by aruanan
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To: Roos_Girl
I read an article yesterday that stated that the CDC had essentially ignored evidence from Denmark that their autism rates fell when they removed mercury from their vaccines.

Probably had good reason to ignore it considering that Denmark’s MMR/mercury & autism researcher Poul Thorsen 49, is going to be extradited "on 13 counts of wire fraud and nine counts of money laundering. This relates to monies paid to Thorsen by the US Centers for Disease Control including for research into the relationship between autism and exposure to vaccines. Thorsen used the stolen money to buy a home in Atlanta, a Harley Davidson motorcycle and two cars, prosecutors said."

Though I note from this link that he supposedly claimed no effect of mercury on autism, there is probably enough squirrelly stuff going on generally to make overall numbers there of children with autism who have had thiomersal in vaccines suspect.

I'm reminded of the researcher here in the U.S. who was the main one getting money from the government for research on ecstasy showing how dangerous it was (which is what they were giving him big bucks to do) and it turned out he was treating the rats with methamphetamine rather than ecstasy.
19 posted on 11/01/2011 2:57:41 PM PDT by aruanan
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To: aruanan

I know this is old, but, if thiomersal were the cause of autism, autism rates should be plunging now that there is much, much, much less thiomersal in vaccinations. Instead, they are exploding even faster, lately.

But I’ve learned that the anti-thiomersal crowd is comprised of exceptionally intelligent people, so I’m wondering if there is a response to this new information.


20 posted on 04/02/2012 4:45:31 AM PDT by dangus
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