[Peet]

A .22lr can be very effective, but at my current age, I've moved up to a 9x18 or a 40cal, for more impact and more ammo at hand.

Bad guy [Russian accent]: Some like the large calibres but I like the point two two. The bullet enters the skull and bounces around turning the brain to mush.

Victim: NNOOOOOOOOOOOOOOOoooooooooooooooooooooo

[bang]

Some TV show, maybe NCIS-LA

[MHGinTN]

When I was younger, at thirty feet or less I aimed for hit spots the size of the eye socket. At sixty-six I aim for the lower pelvis region first, with a few more foot-pounds of impact.