[Secret Agent Man]

They’ve known for a long time DHT kills off hair follicles.

The trick is supressing DHT on the scalp. You can’t get the body to stop making it because it’s a form of testosterone, but if they can prevent it from choking off scalp hair, that’d be great.

[qam1]

They’ve known for a long time DHT kills off hair follicles. The trick is supressing DHT on the scalp.

And they've been wrong for a long time

DHT declines with age, yet the odds of going bald increases. That's a negative correlation. Which is why anti-androgens like propecia and Dutasteride have only a limited effect.

From the article

When the scientists analysed the scalps of balding men, they found levels of PDG2 to be three times higher in areas in which the hair was thinning.

This is where they got the DHT thing wrong. They found in thinning areas DHT was higher than non-thinning and assumed it must be DHT causing the baldness, when in reality it's the opposite in that it is the thinning that is causing the DHT levels to increase (Smaller hair follicle = bigger sebaceous gland = more DHT).

Let's hope the same thing doesn't happen with these PDG2 findings.