[vetvetdoug]

Dogs and wolves can mate resulting in offspring that are capable of producing more offspring. The USDA refers to them as “Hybrids” In Tennessee and Mississippi wolf/dog hybrids are illegal because of the unpredictable nature of the animals. I don't trust coyote/dog or wolf/dog hybrids as they can be intelligent, dangerous and unpredictable. The hybrids also do not react to medicines as do the dogs and paradoxical reactions can occur with many of the common drugs when used in the hybrids. I'm no expert but have always referred to the “wolfdogs” as hybrids that are not sterile.

[Dysart]

Thank you for your input. And it’s interesting that hybrids tend to have paradoxical reactions to drugs. I would imagine that would make them very difficult to treat!