Nuke the entire bay area; with special emphasis on Frisco, Berkley and Marin, they need two 50 megaton weapons each.
Nuke the entire Sacto area, special attention to when every body in the legislature is there for what they call an important vote.
Nuke the entire west side of LA and at least 3 weapons each for West Hollywood and Santa Monica.
This will only give you a fair start on what used to be a pretty decent state, until the wetbacks and homos took over.
I say all of this as a native Californian born in San Francisco.
Reduce those yields to 500 kilotons each and you’re onto something.
You may have already seen this website — but if not then try it out.
http://www.carloslabs.com/node/16
It’s great for working off frustration 8^)