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LSUHSC research finds combo of plant nutrients kills breast cancer cells
Louisiana State University Health Sciences Center ^ | 22-Nov-2013 | Louisiana State University Health Sciences Center

Posted on 11/30/2013 2:55:57 PM PST by xzins

Contact: Leslie Capo lcapo@lsuhsc.edu 504-568-4806 Louisiana State University Health Sciences Center

LSUHSC research finds combo of plant nutrients kills breast cancer cells

New Orleans, LA – A study led by Madhwa Raj, PhD, Research Professor in Obstetrics and Gynecology at LSU Health Sciences Center New Orleans and its Stanley S. Scott Cancer Center, has found that a super cocktail of six natural compounds in vegetables, fruits, spices and plant roots killed 100% of sample breast cancer cells without toxic side effects on normal cells. The results, which also revealed potential treatment target genes, are published in the November 2013 issue of The Journal of Cancer.

"One of the primary causes of both the recurrence of breast cancer and deaths is a small group of cancer stem cells that evade therapy," notes Dr. Raj. "These often multi-drug-resistant cells have the ability to generate new tumors, so it is critically important to develop new approaches to more effective and safer treatment or prevention of breast cancer."

The research team tested ten known protective chemical nutrients found in foods like broccoli, grapes, apples, tofu, and turmeric root (a spice used in Indian curry) before settling upon six – Curcumin known as tumeric, Isoflavone from soybeans, Indo-3-Carbinol from cruciferous plants, C-phycocyanin from spirulina, Reservatrol from grapes, and Quercetin, a flavonoid present in fruits, vegetables, and tea. The researchers administered these six at bioavailable levels to both breast cancer and control cells. They tested the compounds individually and in combination. They found that the compounds were ineffective individually. When combined, though, the super cocktail suppressed breast cancer cell growth by more than 80%, inhibited migration and invasion, caused cell cycle arrest, and triggered the process leading to cell death resulting in the death of 100% of the breast cancer cells in the sample. The researchers observed no harmful effects on the control cells. Further analysis also identified several key genes, which could serve as markers to follow the progress of therapy.

Although the cocktail was not tested against BRCA1 and BRAC2, previous studies have shown that they are molecular targets of four of the six compounds. The researchers also earlier demonstrated that two of the compounds synergize effectively to kill ovarian cancer cells.

According to the National Cancer Institute's SEER Program, which includes data from LSU Health Sciences Center New Orleans, breast cancer is the second most common cancer with 232,340 new cases estimated this year and 39,620 deaths. There are an estimated 2,829,041 women currently living with breast cancer in the United States.

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The LSUHSC research team also included Andrew Hollenbach, PhD, with collaboration from David Welsh, MD, and Udai Pandey, PhD. Other local participants included Drs. Shubha Ireland at Xavier University and Shailaja Raj at Protegene Corporation.

LSU Health Sciences Center New Orleans educates Louisiana's health care professionals. The state's academic health leader, LSUHSC comprises a School of Medicine, the state's only School of Dentistry, Louisiana's only public School of Public Health, and Schools of Allied Health Professions, Nursing, and Graduate Studies. Louisiana's flagship academic health center, LSUHSC faculty take care of patients in public and private hospitals and clinics throughout the region. In the vanguard of biosciences research in a number of areas in a worldwide arena, the LSUHSC research enterprise generates jobs and enormous economic impact. LSUHSC faculty have made lifesaving discoveries and continue to work to prevent, advance treatment, or cure disease. To learn more, visit http://www.lsuhsc.edu and http://www.twitter.com/LSUHSCHealth


TOPICS: News/Current Events
KEYWORDS: breastcancer; breastcancerresearch; cancer; health; research
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Release in LSU Chancellor's Notes:

http://www.lsuhsc.edu/chan_notes/chan_20131122.pdf

1 posted on 11/30/2013 2:55:57 PM PST by xzins
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To: All

The best medical care and research initiatives in the history of the world will be killed by government health monopolies like ObamaCare.


2 posted on 11/30/2013 2:57:22 PM PST by xzins ( Retired Army Chaplain and Proud of It! Those who truly support our troops pray for victory!)
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To: xzins

Well that’s their intention. Obama wants not only the destruction of the country but destruction of the people as well and Obamacare is a very effective way to do it. Just think how close we are to an American Holocaust right now: 80 million people have lost their health insurance. If only 10% of that die as a result, it would be more than the amount of Jews killed by the Nazis. How many people need 24 hour care? How many are in the midst of specialized treatments keeping them alive? How many will lose those treatments? This has the potential for killing Americans that Al-Qaeda could only dream of.


3 posted on 11/30/2013 3:04:50 PM PST by GrandJediMasterYoda (What do we want? Time travel. When do we want it? It's irrelevant.)
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To: xzins

Someone needs to market a tea of these compounds.


4 posted on 11/30/2013 3:12:04 PM PST by txhurl
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To: GrandJediMasterYoda

“The president’s specific words: I’m “really good at killing people,” authors Mark Halperin and John Heilemann write”


5 posted on 11/30/2013 3:17:00 PM PST by Paladin2
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To: txhurl
If it will kill one cancer why not Colon, Prostate, and Testicle Cancer?
6 posted on 11/30/2013 3:24:13 PM PST by SandRat (Duty - Honor - Country! What else needs said?)
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To: Paladin2

And our elected reps won’t even think of impeachment. Let’s see how they feel after a year of this. I don’t even have to guess pretty soon we’re going to hear about people dying because of this nightmare.


7 posted on 11/30/2013 3:25:14 PM PST by GrandJediMasterYoda (What do we want? Time travel. When do we want it? It's irrelevant.)
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To: Paladin2

BRAC2

I hope they test it on BARACK.


8 posted on 11/30/2013 3:25:37 PM PST by Right Wing Assault
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To: xzins
Reservatrol

Is 'reservatrol' different than resveratrol or is the same odd spelling error getting propagated for years and years?
9 posted on 11/30/2013 3:26:04 PM PST by posterchild
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To: SandRat

That’s what I was thinking! Shoot, let’s make our own tea! the ingredients are right in front of us!


10 posted on 11/30/2013 3:28:27 PM PST by txhurl
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To: posterchild
Chancellor's Notes at post #1 spells it:

C-phycocyanin from spirulina, Reservatrol from grapes, and Quercetin, a flavonoid present in fruits, vegetables, and tea

11 posted on 11/30/2013 3:29:54 PM PST by xzins ( Retired Army Chaplain and Proud of It! Those who truly support our troops pray for victory!)
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To: xzins

Thanks, xzins. Other than tofu, these foods, herbs and spices are in my weekly diet. It’s good to know that it’s making such a difference.


12 posted on 11/30/2013 3:31:23 PM PST by trisham (Zen is not easy. It takes effort to attain nothingness. And then what do you have? Bupkis.)
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To: txhurl

If it works we could having 40 yards of farden hose shove up our.... you know.


13 posted on 11/30/2013 3:31:43 PM PST by SandRat (Duty - Honor - Country! What else needs said?)
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To: txhurl
a tea of those compounds

The article doesn't say how the chemical component parts of those plants has to be delivered into the body.

14 posted on 11/30/2013 3:32:21 PM PST by xzins ( Retired Army Chaplain and Proud of It! Those who truly support our troops pray for victory!)
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To: Paladin2

Rainman: “I’m a really good driver”

(or something like that)


15 posted on 11/30/2013 3:33:49 PM PST by xzins ( Retired Army Chaplain and Proud of It! Those who truly support our troops pray for victory!)
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To: xzins

Think the drug companies and doctors will allow the FDA to approve the cocktail? Nah.


16 posted on 11/30/2013 3:38:46 PM PST by huldah1776
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To: xzins

Salad, curry, tea... or were you thinking of main-lining? :)

I love curries, with every animal in them. Just add the rest of the ingredients?


17 posted on 11/30/2013 3:39:49 PM PST by txhurl
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To: huldah1776

The FDA will P&M over something like the word “organic” not being present in the description.


18 posted on 11/30/2013 3:40:30 PM PST by xzins ( Retired Army Chaplain and Proud of It! Those who truly support our troops pray for victory!)
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To: xzins
The article doesn't say how the chemical component parts of those plants has to be delivered into the body.

Well there's the catch.

You have to be able to put your body in a petri dish.

19 posted on 11/30/2013 3:40:45 PM PST by ROCKLOBSTER (Celebrate "Republicans Freed the Slaves" Month.)
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To: txhurl

Yep...could be a mainline cocktail of those specific compounds in megadoses of each. Who knows? My grandson is fighting cancer right now and everything they put in his little body is via a tube.


20 posted on 11/30/2013 3:42:44 PM PST by xzins ( Retired Army Chaplain and Proud of It! Those who truly support our troops pray for victory!)
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