Just my two cents, of course, but I think some attention might be paid to the possibility of a wing root failure of the wing damaged in 2012. I heard one expert, on the television, say that the impact in that incident was enough to knock the vertical stabiliser off an A340. The B777 wing tip was, I am sure, repaired to the satisfaction of BOEING engineers, underwriters, and the Malaysian authorities. Presumably, the entire wing and root structure were exhaustively examined and pronounced OK.
But is it not possible that the impact caused a molecular separation or hot spot in the root that was not visible or detected using dye penetrants, or whatever process the inspectors would use for that purpose? If the root were not re-inspected on a continual basis, a crack may have developed and expanded from this hot spot.
Do you know how many spars the B777 wing uses? Could a crack in the leading edge of the wing root eventually cause the spars to fail?
Losing an entire wing at 500 knots could be so tumultuous as to preclude the pilots’ getting off any transmission, as they would be overwhelmed with trying (in vain) to stabilise the ship.
Losing an entire wing at 500 knots= FOOOM!
Jeff Head's Flickr Photo stream set on MH370
Here's the pic that has been released of potential debris seen by the Vietnamese aircraft: