Name one person who wants to be shot with a .22.
The only self-defense downside of the .22 is it takes too long for the target to bleed out.
Well you don't use the same strategy for a 22 as for a larger caliber. And that was my point - women don't use the same fighting strategy as men, and that's why, IMHO, things hang outside of a guy. God didn't make a mistake - He leveled the playing field.
Actually, the longer I know women, the more I think He made men the underdogs.