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Experimental drug likely saved Ebola patients
CNN ^ | 08/04/2014 | By Dr. Sanjay Gupta and Danielle Dellorto

Posted on 08/04/2014 12:43:15 PM PDT by SeekAndFind

Three vials containing an experimental drug stored at subzero temperatures were flown into Liberia last week in a last-ditch effort to save two American missionary workers who had contracted Ebola, according to a source familiar with details of the treatment.

The drug appears to have worked, sources say. Dr. Kent Brantly's and Nancy Writebol's conditions significantly improved after receiving the medication, sources say. Brantly was able to walk into Emory University Hospital in Atlanta after being evacuated to the United States last week, and Writebol is expected to arrive in Atlanta on Tuesday.

On July 22, Brantly woke up feeling feverish. Fearing the worst, Brantly immediately isolated himself. Writebol's symptoms started three days later. A rapid field blood test confirmed the infection in both of them after they had become ill with fever, vomiting and diarrhea.

It's believed both Brantly and Writebol, who worked with the aid organization Samaritan's Purse, contracted Ebola from another health care worker at their hospital in Liberia, although the official Centers for Disease Control and Prevention case investigation has yet to be released.

A representative from the National Institutes of Health contacted Samaritan's Purse in Liberia and offered the experimental treatment, known as ZMapp, for the two patients, according to the source.

(Excerpt) Read more at cnn.com ...


TOPICS: Culture/Society; Foreign Affairs; Front Page News
KEYWORDS: atlanta; drugs; ebola; ebolacure; ebolapatient; serum

1 posted on 08/04/2014 12:43:15 PM PDT by SeekAndFind
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To: SeekAndFind

bookmark


2 posted on 08/04/2014 12:44:28 PM PDT by dadfly
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To: SeekAndFind

Brantly received a transfusion of the blood of a 14-year-old Ebola survivor who he personally helped to treat. Giving blood transfusions from survivors to still suffering Ebola patients is an established, though not nearly proven, treatment for the largely untreatable disease.

However, on Thursday charity SIM said in a statement that Mrs Writebol’s condition had worsened, despite the serum.

Her husband, David, is close by but can only visit his wife through a window or dressed in a haz-mat suit.

‘We continue to pray for Nancy’s full and complete recovery,’ said Bruce Johnson, president of SIM USA. ‘Even though her condition has worsened, we know she is receiving the best possible medical care, and we are thankful that she has access to this experimental drug.
http://www.freerepublic.com/focus/f-chat/3188888/posts

Funny...two very different updates/stories


3 posted on 08/04/2014 12:45:46 PM PDT by EBH (And the head wound was healed, and Gog became man.)
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To: SeekAndFind
Great so we make enough serum to save conservative Americans and some key European and Israeli friends and we let the disease run it's course making it easy to take over the rest of the world. No! No! Down evil Danny! Down! Down!
4 posted on 08/04/2014 12:48:55 PM PDT by DannyTN (I)
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To: dadfly

That’s RACIST!

LOL! How many of the dead and dying are BLACK? We(USA) save the only 2 WHITE Americans infected????!

Cue the countdown for the outrage from the Race Hustlers at MSNBC, Sharpton, and Jackson.

You can’t make this stuff up.


5 posted on 08/04/2014 12:51:28 PM PDT by LeonardFMason (LanceyHoward would AGREE)
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To: SeekAndFind; All

Post/thread…life/health BUMP!


6 posted on 08/04/2014 12:54:27 PM PDT by PGalt
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To: EBH

Interestingly, I read that there was only one dose of this, and the doctor (Brantley) gave it to the volunteer (Nancy Writebol).

I had read that doctors a few years ago (maybe in Nigeria?) had tried the blood transfusion system and they thought that it had worked. It’s basically the same as any treatment for a disease like this, based on antibodies in the blood of a survivor, but without the intermediate culturing and refining phase.

However, if it’s true that the doctor did not receive the vaccine is doing better while the patient who is doing worse is the one did receive the vaccine, I think the article was not exactly on target.

Furthermore, the doctor was younger, and the two were opposite sexes, so it would be necessary to see what happens with two comparable subjects (i.e., both white males in their 30s or 40s, or both white females in their 50s or 60s).


7 posted on 08/04/2014 1:04:48 PM PDT by livius
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To: EBH

However, on THURSDAY charity SIM said in a statement that Mrs Writebol’s condition had worsened, despite the serum.

*********************************************

Actually, Writebol improved after given a second vial of serum (the report she had worsened was Thursday, the improvement was Sunday):

Writebol also received a vial of the medication. Her response was not as remarkable, according to sources familiar with the treatment. However, doctors on SUNDAY administered Writebol a second dose of the medication, which resulted in significant improvement.

She was stable enough to be evacuated back to the United States and is expected to arrive before noon Tuesday.


8 posted on 08/04/2014 1:08:15 PM PDT by Qiviut ( One of the most delightful things about a garden is the anticipation it provides. (W.E. Johns)
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To: SeekAndFind

Bookmark


9 posted on 08/04/2014 1:10:15 PM PDT by DocRock (All they that TAKE the sword shall perish with the sword. Matthew 26:52 Gun grabbers beware.)
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To: SeekAndFind

Oh God please let it be true; if so, this means that this disease is now both treatable and curable.

This also means that the people who created this are going to get the Nobel Prize and the gratitude of thousands.

If both infected specialists are able to recover, I am certain this will make headlines around the world for months.


10 posted on 08/04/2014 1:12:21 PM PDT by CorporateStepsister (I am NOT going to force a man to make my dreams come true)
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To: livius
Interestingly, I read that there was only one dose of this, and the doctor (Brantley) gave it to the volunteer (Nancy Writebol).

That is what I was lead to think as well. Now it sounds like there was 3 vials? One for Brantly and 2 used on Writebol?

11 posted on 08/04/2014 1:16:53 PM PDT by EBH (And the head wound was healed, and Gog became man.)
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To: All

As the Zen Master said:

“We’ll See.”
.........................
I hope it works.
Although it likely won’t be enough quantity, soon enough to slow the global pandemic that (world and national) government(s) policy is currently enabling.


12 posted on 08/04/2014 1:17:25 PM PDT by LegendHasIt
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To: Qiviut

Thanks for filling in the blanks...

Although I thought there wasn’t enough serum for both of them to begin with, let alone a second dose?

At least that was what earlier reports stated. Brantly gave her the only dose...?


13 posted on 08/04/2014 1:18:20 PM PDT by EBH (And the head wound was healed, and Gog became man.)
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To: SeekAndFind

http://www.foxnews.com/politics/2014/08/04/africa-summit-begins-in-washington-despite-ebola-fears-visitors-face-screening/


14 posted on 08/04/2014 1:43:24 PM PDT by Sacajaweau
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To: EBH

The articles I have read stated that there was a total of three vials brought overseas, but they had to thaw naturally. Dr. Brantly was to be given the first vial (after it thawed), but he offered it to the other victim. But once he took a turn for the worse, it was given to him instead. the other patient was given the second vial (and then the third), after they were fully thawed.

I question the accuracy of the of the original article, I have not read anywhere else regarding this: ... Brantly received a transfusion of the blood of a 14-year-old Ebola survivor who he personally helped to treat. Giving blood transfusions from survivors to still suffering Ebola patients is an established, though not nearly proven, treatment for the largely untreatable disease.

Has anyone else seen this reported anywhere other than this article?


15 posted on 08/04/2014 1:58:24 PM PDT by davandbar
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To: SeekAndFind

E-1011


16 posted on 08/04/2014 2:33:19 PM PDT by NonValueAdded ("Kerry, as Obama's plenipotentiary, is a paradox - the physical presence of a geopolitical absence")
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To: EBH
Although I thought there wasn’t enough serum for both of them to begin with, let alone a second dose? At least that was what earlier reports stated. Brantly gave her the only dose...?

********************************************

Here's the part of this article that clarifies the his/her dose situation (at least 3 doses on hand, issue was thawing) - the first article on this, where he gave her "his" dose, was written in an inaccurate manner, IMO & led you to believe there was only 1 dose between the two of them.

The ZMapp vials reached the hospital in Liberia where Brantly and Writebol were being treated Thursday morning. Doctors were instructed to allow the serum to thaw naturally without any additional heat. It was expected that it would be eight to 10 hours before the medicine could be given, according to a source familiar with the process.

Brantly asked that Writebol be given the first dose because he was younger and he thought he had a better chance of fighting it, and she agreed. However, as the first vial was still thawing, Brantly's condition took a sudden turn for the worse.

Brantly began to deteriorate and developed labored breathing. He told his doctors he thought he was dying, according to a source with firsthand knowledge of the situation.

Knowing his dose was still frozen, Brantly asked if he could have Writebol's now-thawed medication. It was brought to his room and administered through an IV. Within an hour of receiving the medication, Brantly's condition dramatically improved. He began breathing easier; the rash over his trunk faded away. One of his doctors described the events as "miraculous."

By the next morning, Brantly was able to take a shower on his own before getting on a specially designed Gulfstream air ambulance jet to be evacuated to the United States.

Writebol also received a vial of the medication. Her response was not as remarkable, according to sources familiar with the treatment. However, doctors on Sunday administered Writebol a second dose of the medication, which resulted in significant improvement.

17 posted on 08/04/2014 2:46:57 PM PDT by Qiviut ( One of the most delightful things about a garden is the anticipation it provides. (W.E. Johns)
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To: EBH
Funny...two very different updates/stories

Indeed. But what do you expect from the msm these days. It's all magic mirrors and slight of hand. Liars all.

18 posted on 08/04/2014 2:54:19 PM PDT by bgill
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To: Qiviut

bttt


19 posted on 08/04/2014 2:59:11 PM PDT by txhurl (2014: Stunned Voters do Stunning Things!)
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To: EBH
On July 22, Brantly woke up feeling feverish. Fearing the worst, Brantly immediately isolated himself.

That was a Tuesday. Then there's this from his wife's sister in law dated Sunday, July 27, "Amber and their kids arrived back in Texas last week" - http://www.carrollcrossroads.com/ . I still think he shipped his family home on the next plane out when he first suspected/knew he had contracted it.

20 posted on 08/04/2014 3:16:58 PM PDT by bgill
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To: davandbar
Brantly received a transfusion of the blood of a 14-year-old Ebola survivor who he personally helped to treat. Giving blood transfusions from survivors to still suffering Ebola patients is an established, though not nearly proven, treatment for the largely untreatable disease. Has anyone else seen this reported anywhere other than this article?

The 14 year old boy is in numerous stories, and his donation is also mentioned with the experimental drug, the Dr. received both.

21 posted on 08/04/2014 3:33:45 PM PDT by ansel12 (LEGAL immigrants, 30 million 1980-2012, continues to remake the nation's electorate for democrats)
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To: SeekAndFind
This is the experimental "serum" given to the two in Atlanta. They are apparently improving.

Link

22 posted on 08/04/2014 4:42:39 PM PDT by mikey_hates_everything
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To: davandbar; EBH

Interesting, thanks.


23 posted on 08/04/2014 5:19:19 PM PDT by livius
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To: Qiviut

I know. How the stories change. Who to trust?


24 posted on 08/04/2014 8:17:00 PM PDT by MarMema (Run Ted Run)
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To: livius

WBT in Charlotte reported they both took the drug. No link yet. 11PM newscast


25 posted on 08/04/2014 8:27:28 PM PDT by eyedigress ((zOld storarned m chaser from the west)/?s)
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To: 2ndreconmarine; Fitzcarraldo; Covenantor; Mother Abigail; EBH; Dog Gone; ...

Ping...


26 posted on 08/05/2014 1:28:16 AM PDT by Smokin' Joe (How often God must weep at humans' folly. Stand fast. God knows what He is doing.)
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To: LeonardFMason; neverdem; ProtectOurFreedom; Mother Abigail; EBH; vetvetdoug; Smokin' Joe; ...
LOL! How many of the dead and dying are BLACK? We(USA) save the only 2 WHITE Americans infected????!

Not to worry we have our very own FReeper who wants to fix this by bringing every American home to the good ol' USofA for treatment.

I'd name him, but he accuses me of stalking if I dare to....

Bring Out Your Dead

Post to me or FReep mail to be on/off the Bring Out Your Dead ping list.

The purpose of the “Bring Out Your Dead” ping list (formerly the “Ebola” ping list) is very early warning of emerging pandemics, as such it has a high false positive rate.

So far the false positive rate is 100%.

At some point we may well have a high mortality pandemic, and likely as not the “Bring Out Your Dead” threads will miss the beginning entirely.

*sigh* Such is life, and death...

27 posted on 08/05/2014 6:42:17 AM PDT by null and void (If Bill Clinton was the first black president, why isn't Barack Obama the first woman president?)
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To: CorporateStepsister

Yes, let it be true.


28 posted on 08/05/2014 8:07:17 AM PDT by hummingbird (Mark Levin and Article 5. Period. 26 IS THE NEW 18. US = Koyaanisqatsi.)
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To: LegendHasIt
"Although it likely won’t be enough quantity, soon enough to slow the global pandemic that (world and national) government(s) policy is currently enabling."

------------------------->

Israel is very good at developing, manufacturing and dispensing pharmaceuticals.

To use medications from outside US, Israel (or any country) has to partner with a US company so medication can go through FDA process.

If this med works, maybe some country can fast track it without all the paperwork needed up front.

Hope they can - it would be a Godsend.

29 posted on 08/05/2014 8:14:03 AM PDT by hummingbird (Mark Levin and Article 5. Period. 26 IS THE NEW 18. US = Koyaanisqatsi.)
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To: CorporateStepsister

2016 CVS sign:

Flu Vaccine $20
Pneumonia Vaccine $60
Ebola Vaccine $4000
No Appt!

The more you need it the more they charge. Free market at work baby!

/s


30 posted on 08/05/2014 8:26:04 AM PDT by Justa
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Comment #31 Removed by Moderator

To: Tolerance Sucks Rocks

I can’t say...


32 posted on 08/05/2014 7:23:08 PM PDT by null and void (If Bill Clinton was the first black president, why isn't Barack Obama the first woman president?)
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