No, but we were talking about nullification. I still don't see how it works with each state deciding what the federal laws mean.
It may be true that the interpretation of the commerce clause has led to way too many federal laws, but under any interpretation some of them are legit. Did the founders expect them to be ignored by a state just because they didn't agree?
Which level of government do you consider to have proper constitutional authority to regulate intrastate education, health care and drug policies - fedgov or the states?